The effectiveness of Ambu neonatal self-inflating bag to provide consistent positive end-expiratory pressure

Archives of Disease in Childhood. Fetal and Neonatal Edition
M B TracyM Hinder

Abstract

The self-inflating bag (SIB) is the most common device used to resuscitate newborn infants worldwide. Delivering positive end-expiratory pressure (PEEP) may be important in infant resuscitation and limited research using one brand (Laerdal) SIB has led to international guidelines stating SIBs 'often deliver inconsistent positive end-expiratory pressure'. To measure delivered PEEP using disposable and reusable Ambu SIBs fitted with Ambu PEEP valve and manometer comparing different rates of 20, 40 and 60 inflations per minute (IPM) and test lung compliance. Three experienced neonatal medical staff provided positive pressure ventilation each using different disposable and reusable Ambu SIBs, targeting peak inflation pressure of 30-35 cm H2O at three different set PEEP levels of 5, 7.5 and 10 cm H2O on test lungs of compliance of 0.5 and 3.0 mL/cm H2O. Inflation data were captured with Florian Monitor and analysed by analysis of variance for repeated measures. A total of 3265 inflations were analysed. The delivered PEEP was rate and lung compliance dependent. At set PEEP of 5 cm H2O, the adjusted measured PEEP was 3.6, 4.4 and 4.8 cm H2O at rates 20, 40 and 60 IPM, respectively, while at set PEEP of 10 cm H2O, the adjusted measured...Continue Reading

References

Aug 14, 2001·American Journal of Respiratory and Critical Care Medicine·A S NaikM Ikegami
Oct 11, 2001·Journal of Perinatology : Official Journal of the California Perinatal Association·N SinghalY J Yee
Sep 10, 2005·Resuscitation·Sam OddieAndrew Scally
Dec 1, 2009·Journal of Paediatrics and Child Health·Colin J MorleyPeter G Davis
Jun 10, 2010·Archives of Disease in Childhood. Fetal and Neonatal Edition·M B TracyS K Tracy
Apr 1, 2011·Journal of Paediatrics and Child Health·Jennifer A DawsonColin J Morley
Aug 23, 2011·American Journal of Physiology. Lung Cellular and Molecular Physiology·Noah H HillmanAlan H Jobe
Dec 17, 2011·Archives of Disease in Childhood. Fetal and Neonatal Edition·Vadivelam MurthyAnne Greenough
Sep 17, 2013·Seminars in Fetal & Neonatal Medicine·Stuart B HooperArjan B te Pas
May 24, 2014·Lancet·Zulfiqar A BhuttaUNKNOWN Lancet Every Newborn Study Group

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Citations

Dec 25, 2016·Archives of Disease in Childhood. Fetal and Neonatal Edition·Mark TracyMurray Hinder
Aug 31, 2016·Archives of Disease in Childhood. Fetal and Neonatal Edition·Monica ThallingerKetil Størdal
Mar 4, 2018·Archives of Disease in Childhood. Fetal and Neonatal Edition·Marta ThioStuart B Hooper
Oct 22, 2020·Archives of Disease in Childhood. Fetal and Neonatal Edition·Murray HinderMark Brian Tracy
Mar 29, 2021·Seminars in Fetal & Neonatal Medicine·Murray Hinder, Mark Tracy
Jun 18, 2021·Pediatrics·Daniele TrevisanutoUNKNOWN INTERNATIONAL LIAISON COMMITTEE ON RESUSCITATION NEONATAL LIFE SUPPORT TASK FORCE

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