The effects and the mechanism of YSEC-CM on the growth of yolk sac hematopoietic stem/progenitor cells

Leukemia Research
Xiao Dong Na, Qi Ru Wang

Abstract

To explore the distinct background of bone marrow and embryonic yolk sac hematopoiesis performance, serum free murine yolk sac endothelial cell and bone marrow endothelial cell conditioned medium were compared for their effects on the development profiles of yolk sac hematopoietic stem/progenitor cells. The mRNAs expression techniques were applied to understand the cytokine and receptor genes expression and the possible mechanisms. The results suggested that the differential gene expressions were existed between the hematopoietic cells of yolk sac and bone marrow and between the microenvironment of yolk sac and bone marrow.

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Citations

Dec 17, 2003·Current Opinion in Hematology·Ayalew Tefferi, Animesh Pardanani
Apr 23, 2017·Human Brain Mapping·Jessica E Goold, Ming Meng

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