The effects of a treatment combination of anti-VEGF injections, laser coagulation and cryotherapy on patients with type 3 Coat's disease

BMC Ophthalmology
Songfeng LiHai Lu

Abstract

To examined the curative effect of vitreous injection with ranibizumab,laser coagulation and cryotherapy in treating stage 3 Coats' disease with exudative retinal detachment. Seventeen patients with stage 3 Coats' disease were enrolled in the study. All eyes were treated with vitreous injection of ranibizumab as initial treatment, and subsequent treatment depended on the absorption of subretinal fluid, Including cryotherapy and laser photocoagulation. Repeat treatment for the two treatment intervals occurred in ≥1 month. The mean follow-up time was 24.12 ± 5.99 months. The main data evaluation and outcome measurements included the patient's vision, intraocular pressure(IOP), optical coherence tomography (OCT), slit lamp examination, indirect ophthalmoscopy, color Doppler imaging (CDI) and color fundus image analysis. The following variables were compared between groups: abnormal vascular changes, subretinal fluid and exudate absorption, retinal reattachment and complications. The final follow-up results were used to determine the effectiveness of treatment. Of the 17 patients included, 88.24% were male and 11.76% were female. Visual acuity was less than 0.02 in 12 eyes before surgery and 8 eyes after surgery. Visual acuity impr...Continue Reading

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Citations

Mar 13, 2018·Retina·Mrinali P GuptaR V Paul Chan
Apr 9, 2020·International Journal of Molecular Sciences·Tamás Kovács-ÖllerBotir T Sagdullaev
Mar 22, 2019·International Ophthalmology·Xinyue YangGuanfang Su
Jul 30, 2019·Asia-Pacific Journal of Ophthalmology·Chloe T L KhooCarol L Shields
Jan 29, 2021·International Journal of Molecular Sciences·Arunbalaji PugazhendhiBalamurali Ambati
Jan 5, 2021·World Journal of Clinical Cases·Li JiangHui-Qin Yang
Jan 1, 2021·Oxidative Medicine and Cellular Longevity·Lei Xi
Mar 27, 2021·European Journal of Ophthalmology·Ashok KumarSanjay Kumar Mishra
Jan 9, 2020·Retinal Cases & Brief Reports·Carlos Plaza-LaguardiaRoberto Gallego-Pinazo

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