The effects of acute leucine or leucine-glutamine co-ingestion on recovery from eccentrically biased exercise

Amino Acids
Mark WaldronStephen David Patterson

Abstract

This study investigated the effects of leucine or leucine + glutamine supplementation on recovery from eccentric exercise. In a double-blind independent groups design, 23 men were randomly assigned to a leucine (0.087 g/kg; n = 8), leucine + glutamine (0.087 g/kg + glutamine 0.3 g/kg; n = 8) or placebo (0.3 g/kg maltodextrin; n = 7) group. Participants performed 5 sets of drop jumps, with each set comprising 20 repetitions. Isometric knee-extensor strength, counter-movement jump (CMJ) height, delayed-onset muscle soreness (DOMS) and creatine kinase (CK) were measured at baseline, 1, 24, 48 h and 72 h post-exercise. There was a time × group interaction for isometric strength, CMJ and CK (P < 0.05), with differences between the leucine + glutamine and placebo group at 48 h and 72 h for strength (P = 0.013; d = 1.43 and P < 0.001; d = 2.06), CMJ (P = 0.008; d = 0.87 and P = 0.019; d = 1.17) and CK at 24 h (P = 0.012; d = 0.54) and 48 h (P = 0.010; d = 1.37). The leucine group produced higher strength at 72 h compared to placebo (P = 0.007; d = 1.65) and lower CK at 24 h (P = 0.039; d = 0.63) and 48 h (P = 0.022; d = 1.03). Oral leucine or leucine + glutamine increased the rate of recovery compared to placebo after eccentric exerci...Continue Reading

References

Dec 1, 1981·The Journal of Clinical Investigation·T T AokiD C Knight
Feb 11, 2000·Journal of Science and Medicine in Sport·R L Lieber, J Fridén
Jun 20, 2001·Acta Physiologica Scandinavica·H Gissel, T Clausen
Sep 10, 2002·American Journal of Physiology. Endocrinology and Metabolism·Elisabet BørsheimRobert R Wolfe
Mar 6, 2003·Sports Medicine·Karoline CheungLinda Maxwell
Dec 21, 2005·The Journal of Nutrition·Eva BlomstrandRickard Köhnke
May 21, 2008·Sports Medicine·Glyn Howatson, Ken A van Someren
Jul 9, 2008·Journal of Sports Sciences·Craig TwistRoger Eston
Jul 19, 2008·Nutrition & Metabolism·Nelo E ZanchiAntonio H Lancha
Jul 16, 2009·Journal of Nutritional Science and Vitaminology·Yoshiharu ShimomuraJuichi Sato
Nov 3, 2009·Amino Acids·Philip J AthertonMichael J Rennie
Dec 10, 2009·Medicine and Science in Sports and Exercise·Sarah R JackmanKevin D Tipton
Jan 19, 2010·Muscle & Nerve·Igor L BaptistaAnselmo S Moriscot
Jul 17, 2010·Journal of Strength and Conditioning Research·Matt S StockTravis W Beck
Sep 18, 2010·Journal of Strength and Conditioning Research·Brad J Schoenfeld
Dec 16, 2011·Journal of the International Society of Sports Nutrition·Claudia R da LuzAntonio H Lancha
Feb 22, 2012·Journal of Strength and Conditioning Research·Brad J Schoenfeld
Mar 27, 2015·International Journal of Sport Nutrition and Exercise Metabolism·Zachary LegaultDerek S Kimmerly
Feb 9, 2017·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Mark WaldronStephen David Patterson

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Citations

Feb 16, 2021·The Journal of Sports Medicine and Physical Fitness·Alejandra Arroyo-CerezoMaría-Soledad Fernández-Pachón

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