PMID: 2497643May 1, 1989Paper

The effects of administration of lithium salts and magnesium sulfate on the serum anion gap

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
F J SilversteinC A Vaamonde

Abstract

Whether or not an increased serum level of an unmeasured cation will reduce the anion gap (AG) depends on concomitant changes (or lack thereof) in serum unmeasured anions. In the present retrospective study, we sought to determine the effect of lithium carbonate or citrate and magnesium sulfate on the AG. Two groups of psychiatric patients whose average serum lithium levels were 0.6 and 1.0 mEq/L were studied. The AG in each group (10.2 +/- 0.3 [SE] and 9.0 +/- 0.4 mEq/L, respectively) was significantly (P less than 0.05) lower than that of a control group (11.1 +/- 0.3 mEq/L). Separately, we collected 87 pairs of AG and serum magnesium data of patients with toxemia of pregnancy. These included those of 15 patients evaluated both before and during magnesium sulfate infusion. Despite an average serum magnesium level of 4.1 +/- 0.2 mEq/L, the AG of the latter subjects tended to increase slightly from 10.8 +/- 0.5 to 11.7 +/- 0.7 mEq/L during magnesium infusion, instead of decreasing. The other data (72 determinations in the 55 patients without preinfusion values) revealed a mean AG of 11.0 +/- 0.3 mEq/L, coexisting with an elevated serum magnesium of 4.1 +/- 0.1 mEq/L. None of the above-mentioned three mean AG values differed sig...Continue Reading

References

Oct 13, 1977·The New England Journal of Medicine·M S Oh, H J Carroll
Feb 1, 1985·Kidney International·P A Gabow
Sep 1, 1986·Archives of Internal Medicine·S P KelleherL A Arbeit
Feb 1, 1988·Southern Medical Journal·J R OsterB J Materson
Sep 1, 1987·Digestive Diseases and Sciences·G O PerezA Rogers
Mar 10, 1988·The New England Journal of Medicine·D C BatlleR Gupta
Oct 1, 1986·The American Journal of the Medical Sciences·M B GoldsteinM L Halperin
Dec 5, 1985·The New England Journal of Medicine·K Godfrey

❮ Previous
Next ❯

Citations

Sep 14, 2015·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Michael Emmett
Dec 1, 1993·Annals of Emergency Medicine·R J RobergeS M Schneider
Jan 1, 1992·Journal of Toxicology. Clinical Toxicology·J P RuizT V Brigger
Aug 21, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Jeffrey A Kraut, Nicolaos E Madias
Dec 9, 2000·American Journal of Respiratory and Critical Care Medicine·V FenclJ Figge
Jan 19, 1999·The American Journal of the Medical Sciences·J R OsterC F Vieira

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.