PMID: 9420666Jan 1, 1994Paper

The effects of afterload reduction on myocardial carbon 11-labeled acetate kinetics and noninvasively estimated mechanical efficiency in patients with dilated cardiomyopathy

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
Rob S BeanlandsM Schwaiger

Abstract

With echocardiography and dynamic carbon 11-labeled acetate (C-11 acetate) positron emission tomographic imaging, C-11 acetate kinetics and a parameter that estimates mechanical ventricular efficiency (the work metabolic index) were defined in eight patients with dilated cardiomyopathy. The effect of afterload reduction with nitroprusside on these parameters was evaluated in six of these patients. Nitroprusside increased stroke work index but decreased the C-11 clearance rate. The work metabolic index determined noninvasively increased and correlated well with an invasive approach. The work metabolic index was inversely correlated with systemic vascular resistance. Nitroprusside shifted this relationship upward and to the left. This method of estimating efficiency is feasible and may represent a unique noninvasive approach for the evaluation of cardiac performance and responses to therapy.

References

Oct 1, 1975·British Heart Journal·F WaagsteinI Wallentin
Mar 1, 1992·Circulation·T KameyamaS Sasayama
Aug 1, 1991·The New England Journal of Medicine·UNKNOWN SOLVD InvestigatorsJay N Cohn
Mar 1, 1989·Journal of the American College of Cardiology·A M Katz
Mar 1, 1989·Journal of the American College of Cardiology·M G SpainA N DeMaria
Sep 1, 1988·Circulation Research·D B BuxtonH R Schelbert
Oct 1, 1988·Journal of the American College of Cardiology·M A BrownS R Bergmann
Feb 1, 1986·Journal of the American College of Cardiology·A B NicholsP J Cannon
Feb 1, 1986·Journal of the American College of Cardiology·J S Karliner
Jul 1, 1982·The International Journal of Applied Radiation and Isotopes·V W PikeA P Selwyn
Mar 1, 1981·Basic Research in Cardiology·D BallerG Hellige
Jan 1, 1962·The American Journal of Cardiology·R C SCHLANTR J ROBERTSON

❮ Previous
Next ❯

Citations

May 1, 1994·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·H G WolpersM Schwaiger
May 1, 1995·Journal of the American College of Cardiology·D S BachW F Armstrong
Jun 10, 2005·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Pilar Herrero, Robert J Gropler
Aug 22, 2006·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Marvin W KronenbergMarcelo F Di Carli
Jul 11, 2000·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·O Akinboboye, S R Bergmann
Feb 4, 2014·Current Cardiovascular Imaging Reports·Masanao Naya, Nagara Tamaki
Dec 18, 2013·Journal of Cardiac Failure·Susan P BellMarvin W Kronenberg
Feb 11, 2005·European Journal of Heart Failure·Oliver LindnerWolfgang Burchert
Apr 21, 2016·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Nils Henrik HanssonJens Sørensen
Mar 3, 2010·Circulation. Cardiovascular Imaging·Benjamin J W ChowTerrence D Ruddy
Nov 1, 2007·Journal of Cardiovascular Electrophysiology·Stuart D ChristensonRaymond J Gibbons
Aug 12, 2018·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Frank M Bengel
Aug 7, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Markus Schwaiger, Stephan G Nekolla
Jun 2, 2018·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Nils Henrik HanssonJens Sörensen
Oct 22, 2020·Journal of Cardiovascular Imaging·In Chang Hwang
Nov 11, 2020·Journal of the American Heart Association·Evan L BrittainAnna R Hemnes
Jun 17, 2020·Seminars in Nuclear Medicine·Gedaliah FarberBenjamin H Rotstein
Jun 3, 2021·International Journal of Molecular Sciences·Dianne M Perez
Nov 10, 2021·European Heart Journal Cardiovascular Imaging·Kristoffer Berg HansenHenrik Wiggers

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.