Abstract
Mesenchymal stem cells (MSCs) have a great capacity for use in regenerative medicine and other clinical applications. However, one question creating curiosity of their use, is how they are affected by ageing. As we now live within an ageing population, the prevalence of age related disorders is increasing, so it is important to investigate how effectively MSCs from older patients can be expanded and differentiated in vitro before their use in autologous cell transplantation. This paper will look at how ageing effects proliferation potential, differentiation potential and cell surface characterisation of human mesenchymal stem cells.
Citations
Mar 21, 2012·PloS One·Stefania BrunoGiovanni Camussi
Oct 3, 2012·PloS One·Maria BrohlinMikael Wiberg
Mar 13, 2013·Regenerative Medicine·Ursula StochajInés Colmegna
Jan 1, 2016·Stem Cell Research & Therapy·Loïc ReppelCéline Huselstein
Dec 21, 2014·Cell Stress & Chaperones·Fatemeh AmiriMehryar Habibi Roudkenar
Dec 10, 2016·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Benjamin M DaviesAndrew J Price
Mar 2, 2017·Diabetes·Julie A HaywardGregory S Korbutt
Apr 4, 2017·Journal of Cellular Physiology·Eiman Abdel MeguidAhmed H K El-Hashash
Sep 25, 2019·Cells·Eleonora MazzottiAurelio Muttini
May 29, 2020·Orthopaedic Surgery·Yanhong ZhaoQiang Yang
Jul 6, 2017·Stem Cell Research & Therapy·Léonore Avercenc-LégerLoïc Reppel
Jun 27, 2020·Stem Cells International·Han-Sung Hwang, Yong-Sun Maeng
Aug 25, 2017·Stem Cells International·Katsunori ShiraishiMitsuo Ochi
May 24, 2019·Aging Cell·Dongdong FeiYan Jin
Apr 4, 2021·Cells·Ewelina TomeckaNatalia Rozwadowska
Jul 3, 2021·Cells·Nikhil AgarwalWasim Khan