The effects of alcohol consumption on ambulatory blood pressure and target organs in subjects with borderline to mild hypertension. HARVEST Study Group

American Journal of Hypertension
O VrizP Palatini

Abstract

The objective of this study was to examine the relationship of alcohol consumption to target organ involvement and ambulatory blood pressure (BP) in a population of young borderline to mild hypertensive subjects. Participants were 793 male subjects, aged 18-45 years, from the HARVEST Study. The analysis was performed in three age-matched groups with similar body mass index. Casual and 24-h ambulatory BP monitoring, routine biochemistry, echocardiography, and albumin excretion rate were measured. The men were divided into three groups: 1) nondrinkers, 2) drinkers of < 50 g/day, and 3) drinkers of > or = 50 g/day. Office systolic BP was not significantly different among the three groups, whereas 24-h and daytime BPs increased progressively from the first to the third group (group 1 v 3; P = .01 for 24-h systolic BP and P = .02 for daytime systolic BP). These differences remained significant even after adjusting for smoking. Left ventricular mass index, interventricular septum thickness, and wall thickness increased progressively from group 1 to group 3; this difference also remained significant after adjusting for smoking and 24-h BPs. The albumin excretion rate was much higher in group 3 than in group 1 (P = .003), but when 24-h...Continue Reading

Citations

Jun 12, 2003·Blood Pressure·Raquel Hernández del-ReyHelios Pardell
Feb 24, 2006·Blood Pressure Monitoring·Daniele LongoPaolo Palatini
Feb 26, 2016·High Blood Pressure & Cardiovascular Prevention : the Official Journal of the Italian Society of Hypertension·Rosa Maria BrunoMartino Francesco Pengo
Oct 21, 2000·American Journal of Hypertension·J M Ryan, L G Howes
Aug 5, 2000·The Journal of the Royal Society for the Promotion of Health·J A PapadakisD P Mikhailidis
Nov 27, 2004·Blood Pressure Monitoring·Paolo Palatini
May 22, 2010·American Journal of Hypertension·Jerome L AbramsonNancy V Murrah
Feb 7, 2014·High Blood Pressure & Cardiovascular Prevention : the Official Journal of the Italian Society of Hypertension·Paolo Palatini
Sep 1, 2007·Blood Pressure Monitoring·Willem J VerberkPeter W de Leeuw
Aug 10, 2005·The Journal of Clinical Hypertension·Peter M MillerShaun A Nguyen
Jan 22, 2011·Journal of Hypertension·Dagmara HeringKrzysztof Narkiewicz

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