The effects of an exercise program on fall risk factors in people with Parkinson's disease: a randomized controlled trial

Movement Disorders : Official Journal of the Movement Disorder Society
Natalie E AllenVictor S C Fung

Abstract

This randomized controlled trial with blinded assessment aimed to determine the effect of a 6-month minimally supervised exercise program on fall risk factors in people with Parkinson's disease (PD). Forty-eight participants with PD who had fallen or were at risk of falling were randomized into exercise or control groups. The exercise group attended a monthly exercise class and exercised at home three times weekly. The intervention targeted leg muscle strength, balance, and freezing. The primary outcome measure was a PD falls risk score. The exercise group had no major adverse events and showed a greater improvement than the control group in the falls risk score, which was not statistically significant (between group mean difference = -7%, 95% CI -20 to 5, P = 0.26). There were statistically significant improvements in the exercise group compared with the control group for two secondary outcomes: Freezing of Gait Questionnaire (P = 0.03) and timed sit-to-stand (P = 0.03). There were statistically nonsignificant trends toward greater improvements in the exercise group for measures of muscle strength, walking, and fear of falling, but not for the measures of standing balance. Further investigation of the impact of exercise on fal...Continue Reading

Associated Clinical Trials

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Aug 1, 1989·Clinical Neuropharmacology·W C KollerR Barter
Jun 1, 1995·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·V PetoR Greenhall
Oct 1, 1994·Journal of the American Geriatrics Society·S R LordK J Anstey
Mar 1, 1996·Archives of Physical Medicine and Rehabilitation·S R LordP Williams
May 19, 2000·Parkinsonism & Related Disorders·N GiladiA D Korczyn
Jan 4, 2001·American Journal of Physical Medicine & Rehabilitation·T A ScandalisM R Wells
Jan 5, 2002·Journal of Neurology·B R BloemA H Zwinderman
Apr 5, 2002·Archives of Physical Medicine and Rehabilitation·Andrea L BehrmanMary T Thigpen
May 2, 2002·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Graziano OnderMarco Pahor
May 23, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·B H WoodR W Walker
May 25, 2002·Journal of the American Geriatrics Society·M Clare RobertsonNancy Devlin
May 2, 2003·Movement Disorders : Official Journal of the Movement Disorder Society·Allan L AdkinMandar S Jog
Aug 15, 2003·Archives of Physical Medicine and Rehabilitation·Mark A HirschRobert A Rider
Feb 18, 2004·Archives of Physical Medicine and Rehabilitation·Louisa S DeBolt, Jeffrey A McCubbin
Apr 17, 2004·Journal of the American Geriatrics Society·Teresa Liu-AmbroseHeather A McKay
Jul 13, 2004·Current Opinion in Neurology·Yvette A M GrimbergenBastiaan R Bloem
Mar 4, 2005·Disability and Rehabilitation·Christine DaveyCaroline Murphy
Sep 13, 2005·Parkinsonism & Related Disorders·F FranchignoniC Pasetti
Nov 8, 2005·Parkinsonism & Related Disorders·Anette SchragMarjan Jahanshahi
Jun 15, 2006·Movement Disorders : Official Journal of the Movement Disorder Society·Leland E DibblePaul C LaStayo
Jul 27, 2006·Internal Medicine Journal·J A Temlett, P D Thompson
Nov 23, 2006·Journal of Neurology, Neurosurgery, and Psychiatry·Ann AshburnCarolyn Fitton
Jan 19, 2007·Journal of Neurology, Neurosurgery, and Psychiatry·A NieuwboerI Lim
Jan 9, 2008·Movement Disorders : Official Journal of the Movement Disorder Society·Victoria A GoodwinJohn L Campbell
Oct 23, 2008·Movement Disorders : Official Journal of the Movement Disorder Society·Meg E MorrisBeth Kirkwood
Dec 20, 2008·Journal of the American Geriatrics Society·Catherine SherringtonJacqueline C T Close
Mar 7, 2009·Journal of Neurologic Physical Therapy : JNPT·Leland E DibbleEvan Papa
May 9, 2009·Movement Disorders : Official Journal of the Movement Disorder Society·Mark D LattVictor S C Fung

❮ Previous
Next ❯

Citations

Jan 19, 2013·Journal of Neural Transmission·Elke HeremansS Vercruysse
Jun 19, 2013·Lancet Neurology·Giselle M PetzingerMichael W Jakowec
Jul 14, 2011·Nature Reviews. Neurology·Arlène D SpeelmanBastiaan R Bloem
Jun 8, 2012·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·S BohlenR Reilmann
Jan 3, 2013·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·J J FerreiraW H Oertel
Aug 8, 2012·BMJ : British Medical Journal·Claire L TomlinsonNatalie Ives
May 3, 2012·Parkinson's Disease·Gammon M EarhartLeland E Dibble
Mar 15, 2013·Neuropsychiatric Disease and Treatment·David J Pedrosa, Lars Timmermann
Aug 7, 2014·Neurodegenerative Disease Management·Colleen G CanningAlice Nieuwboer
Dec 2, 2014·Journal of Physical Therapy Science·Hideyuki Nakae, Hitoshi Tsushima
Dec 3, 2013·ISRN Neurology·Hye-Jung ChoiHyun-Joo Kang
Jul 9, 2016·Journal of Physical Therapy Science·Jamile Benite Palma LopesClaudia Santos Oliveira
Jul 19, 2016·Canadian Journal on Aging = La Revue Canadienne Du Vieillissement·Symron BansalLora M Giangregorio
Oct 26, 2016·PM & R : the Journal of Injury, Function, and Rehabilitation·Chad SwankSimon Driver
Jun 26, 2014·Neurorehabilitation and Neural Repair·Janey ProdoehlJulie A Robichaud
Oct 1, 2011·Neurorehabilitation and Neural Repair·Ryan P Duncan, Gammon M Earhart
Oct 24, 2015·Neurorehabilitation and Neural Repair·Xia ShenMargaret K Y Mak
Apr 11, 2014·Western Journal of Nursing Research·Juhee LeeJinyong Hong
Jun 19, 2016·Clinical Nursing Research·JuHee LeeYonju Yoo
Jun 1, 2016·Home Healthcare Now·Teri Capriotti, Kristina Terzakis
Sep 29, 2018·Neurorehabilitation and Neural Repair·Meng NiCorneliu Luca
Mar 19, 2019·Journal of Neurologic Physical Therapy : JNPT·Ryan P HubbleMichael H Cole
Jan 19, 2018·Rehabilitation Nursing : the Official Journal of the Association of Rehabilitation Nurses·JuHee LeeJi Yong Byun
Oct 14, 2017·Nature Reviews. Neurology·Margaret K MakChloe L Chung
May 3, 2019·Technology and Health Care : Official Journal of the European Society for Engineering and Medicine·Sukwon KimJee-Hoon Sohn
Sep 11, 2013·The Cochrane Database of Systematic Reviews·Claire L TomlinsonNatalie Ives
Oct 18, 2013·Movement Disorders : Official Journal of the Movement Disorder Society·Nicolien M van der Kolk, Laurie A King
Feb 11, 2014·American Journal of Physical Medicine & Rehabilitation·Gavin WilliamsAlana Randall
Dec 31, 2015·Movement Disorders : Official Journal of the Movement Disorder Society·Gretchen O ReynoldsAlice Cronin-Golomb

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.