The effects of colestipol hydrochloride on serum lipoprotein lipid and apolipoprotein B and A-I concentrations in children heterozygous for familial hypercholesterolemia

Acta paediatrica Scandinavica
P H GrootJ Fernandes

Abstract

The effects of colestipol hydrochloride on serum lipoprotein lipid and apolipoprotein B and A-I concentrations in children heterozygous for familial hypercholesterolemia. Acta Paediatr Scand, 72:81, 1983.--Colestipol hydrochloride was administered to 28 children with familial hypercholesterolemia type II-A, and its effects on serum lipoproteins were tested against a placebo in a cross-over design. All children consumed a diet low in cholesterol and high in linoleic acid. Colestipol therapy resulted in a 15.7% decrease in serum very low plus low density lipoproteins and in a 13.5% decrease in serum apolipoprotein B. High density lipoprotein cholesterol, serum apolipoprotein A-I and serum triglycerides remained unaltered.

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Citations

Jan 1, 1991·Annals of the New York Academy of Sciences·J M Hoeg
May 6, 2015·Cardiology Clinics·Patrick M Moriarty, Linda Hemphill
Jul 1, 1984·Journal of Chemical Ecology·E Vernet-MauryA Demael
Sep 1, 2008·Expert Review of Endocrinology & Metabolism·Lorenzo IughettiFiorella Balli

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