The Effects of Fermented Laminaria japonica on Short-Term Working Memory and Physical Fitness in the Elderly

Evidence-based Complementary and Alternative Medicine : ECAM
Storm N S ReidByeong Hwan Jeon

Abstract

Considering the neuroprotective and antioxidant potential of fermented Laminaria japonica A. (FST), the purpose of the present study is to establish whether FST may be considered a viable, efficacious supplement that can be administered in later life to offset neurodegenerative conditions associated with aging. Forty senior subjects participated in a randomized, double-blind, and placebo-controlled study. Two groups were formed, one FST group (n = 32, 72.35 ± 5.54 yrs) and one placebo (CON) (n = 28, 74.57 ± 5.69 yrs), which received 1.5 g/day of FST for 6 weeks. Subjects were asked to abstain from any regular exercise. In order to analyze short-term memory, a variety of neuropsychological tests were implemented. Body composition, physical fitness evaluations, antioxidant function, and inflammatory markers were also included in the analyses pre- and posttest. We demonstrated that FST significantly improved neuropsychological test scores, including higher scores in the K-MMSE, numerical memory test, Raven test, and iconic memory, compared to the CON group. Shorter test trial times in the 6-minute walk test were observed in the FST group (p<0.001 and p<0.05, trials 1 and 2, respectively). FST also significantly increased antioxida...Continue Reading

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Citations

Mar 4, 2020·Marine Drugs·Nuri GuevenJ Helen Fitton
Apr 9, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·Erica Shih-Wei HungChien-Hung Lai
Oct 3, 2018·Evidence-based Complementary and Alternative Medicine : ECAM·Storm N S ReidByeong Hwan Jeon
Aug 28, 2021·Nutrients·Hellen A Oketch-RabahJoseph M Betz

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Methods Mentioned

BETA
MDA
Assay
enzyme-linked immunosorbent assay

Software Mentioned

Statistical Package for Social Sciences ( SPSS

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