The effects of hypoxia and fatigue on skeletal muscle electromechanical delay.

Experimental Physiology
Mark Jacunski, Gerrard F Rafferty

Abstract

What is the central question of this study? What are the mechanisms underlying impaired muscular endurance and accelerated fatigue during acute hypoxia? What is the main finding and its importance? Hypoxia had no effect on the electrochemical latency associated with muscle contraction elicited by supramaximal electrical motor nerve stimulation in vivo. This provides greater insight into the effects of hypoxia and fatigue on the mechanisms of muscle contraction in vivo. Acute hypoxia impairs muscle endurance and accelerates fatigue, but the underlying mechanisms, including any effects on muscle electrical activation, are incompletely understood. Electromyographic, mechanomyographic and force signals, elicited by common fibular nerve stimulation, were used to determine electromechanical delay (EMDTOT ) of the tibialis anterior muscle in normoxia and hypoxia ( F I O 2 0.125) at rest and following fatiguing ankle dorsiflexor exercise (60% maximum voluntary contraction, 5 s on, 3 s off) in 12 healthy participants (mean (SD) age 27.4 (9.0) years). EMDTOT was determined from electromyographic to force signal onset, electrical activation latency from electromyographic to mechanomyographic (EMDE-M ) and mechanical latency from mechan...Continue Reading

References

Nov 1, 1979·European Journal of Applied Physiology and Occupational Physiology·P R Cavanagh, P V Komi
Mar 1, 1990·Journal of Applied Physiology·S H GarnerC S Houston
Jul 1, 1983·Experimental Neurology·A A VandervoortA J McComas
Jan 1, 1995·European Journal of Applied Physiology and Occupational Physiology·M Petitjean, B Maton
Sep 1, 1993·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·R W GrangeM E Houston
Nov 1, 1996·Journal of Applied Physiology·C S FulcoK B Pandolf
Mar 31, 1999·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·C OrizioA Veicsteinas
Sep 6, 2001·Journal of Neurophysiology·L Q Zhang, W Z Rymer
Feb 1, 2003·European Journal of Applied Physiology·Isabelle MoraPérot Chantal
Feb 1, 2003·European Journal of Applied Physiology·Claudio OrizioMoshe Solomonow
Jul 24, 1950·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·A V HILL
Dec 24, 2005·Muscle & Nerve·Hans DegensMaria T E Hopman
Mar 8, 2007·Pflügers Archiv : European journal of physiology·Peter G Martin, Jodie Rattey
Apr 28, 2007·The International Journal of Neuroscience·J Ty HopkinsIain Hunter
Jun 5, 2007·Experimental Physiology·Richard A Howlett, Michael C Hogan
Jun 5, 2007·Medicine and Science in Sports and Exercise·Christoph SzubskiWolfgang N Löscher
Oct 9, 2007·Exercise and Sport Sciences Reviews·Marc Vanderthommen, Jacques Duchateau
Oct 27, 2007·Journal of Applied Physiology·Markus Amann, Jose A L Calbet
Oct 30, 2007·Respiratory Physiology & Neurobiology·Barbara J LutjemeierThomas J Barstow
Jun 13, 2009·High Altitude Medicine & Biology·Stéphane Perrey, Thomas Rupp
Jun 27, 2009·High Altitude Medicine & Biology·Markus Amann, Bengt Kayser
May 1, 2010·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·S Utku YavuzKemal S Türker
May 18, 2010·European Journal of Applied Physiology·Nicola A Maffiuletti
Sep 19, 2012·Muscle & Nerve·John M SeymourGerrard F Rafferty
Mar 7, 2013·Muscle & Nerve·Emiliano CèFabio Esposito
Dec 24, 2013·European Journal of Applied Physiology·Susanna RampichiniFabio Esposito
Jun 15, 2014·Experimental Physiology·Matthew MaddocksGerrard F Rafferty
Sep 17, 2014·High Altitude Medicine & Biology·Rafael Torres-PeraltaJosé A L Calbet
Dec 3, 2014·Autonomic Neuroscience : Basic & Clinical·Markus AmannMassimo Venturelli
Jun 19, 2015·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Chris J McNeilCharles L Rice
Nov 10, 2015·Respiratory Physiology & Neurobiology·Andrew J O'Leary, Ken D O'Halloran
Jun 10, 2016·High Altitude Medicine & Biology·Jui-Lin Fan, Bengt Kayser
Dec 10, 2016·Muscle & Nerve·Cory M SmithRichard J Schmidt
Feb 9, 2017·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Cory M SmithRichard J Schmidt
Jul 26, 2019·Current Opinion in Physiology·Christopher W Sundberg, Robert H Fitts

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.