The effects of hysterectomy with bilateral salpingectomy on ovarian reserve

International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
Zhen YuanKeng Shen

Abstract

To determine whether ovarian reserve is compromised after hysterectomy with bilateral salpingectomy. A prospective longitudinal study was conducted among 84 women who underwent hysterectomy with bilateral salpingectomy at a tertiary medical center in Beijing, China, between August 2, 2015, and January 15, 2017. Serum levels of anti-Müllerian hormone (AMH) and follicle-stimulating hormone (FSH) were measured to assess ovarian function before undergoing the procedure (baseline) and at weeks 1 and 6 after surgery (postoperative period). The median age was 41.61 ± 0.62 years. Age negatively correlated with the serum AMH level at baseline (P<0.001), as well as with preoperative-to-postoperative changes in the concentration of this hormone (P<0.001). Serum AMH levels were lower in the postoperative period versus the preoperative period (P<0.001). By contrast, serum FSH levels were higher in the postoperative period than in the preoperative period (P<0.001). Moreover, no correlation was found with body mass index. Hysterectomy with bilateral salpingectomy compromised ovarian reserve, with the damage being most severe among younger patients.

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Citations

Apr 8, 2020·Journal of Obstetrics and Gynaecology of India·Suvarna Khadilkar

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