The Effects of Oral Taurine on Resting Blood Pressure in Humans: a Meta-Analysis

Current Hypertension Reports
Mark WaldronOwen Jeffries

Abstract

The aims of this meta-analysis were to investigate the effects of orally administered isolated taurine on resting systolic blood pressure (SBP) and diastolic blood pressure (DBP) in humans. There is growing evidence that taurine deficiency is associated with hypertension and that oral supplementation can have antihypertensive effects in humans. However, these investigations have been conducted across a number of decades and populations and have not been collectively reviewed. A search was performed using various databases in May 2018 and later screened using search criteria for eligibility. There were seven peer-reviewed studies meeting the inclusion criteria, encompassing 103 participants of varying age and health statuses. Taurine ingestion reduced SBP (Hedges' g = - 0.70, 95% CI - 0.98 to - 0.41, P < 0.0001) and DBP (Hedges' g = - 0.62, 95% CI - 0.91 to - 0.34, P < 0.0001). These results translated to mean ~ 3 mmHg reductions in both SBP (range = 0-15 mmHg) and DBP (range = 0-7 mmHg) following a range of doses (1 to 6 g/day) and supplementation periods (1 day to 12 weeks), with no adverse events reported. These preliminary findings suggest that ingestion of taurine at the stated doses and supplementation periods can reduce b...Continue Reading

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Citations

Sep 29, 2019·Canadian Journal of Physiology and Pharmacology·Ghassan BkailyDanielle Jacques
Sep 5, 2019·Amino Acids·Mark WaldronOwen Jeffries
May 7, 2020·Scientific Reports·Yaya GoïtaPascal Reynier
Jun 18, 2020·Nutrients·Chien-Ning Hsu, You-Lin Tain
Jun 18, 2021·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Mahedeh SamadiMohammad Abdollahi

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