The effects of preemptive analgesia of morphine and ketorolac on postoperative pain, cortisol, O(2) saturation and heart rate

Journal of Korean Academy of Nursing
Yun Ju Seo, Hae Sang Yoon

Abstract

This study investigated the preemptive analgesic effects of Morphine and Ketorolac on postoperative pain, cortisol, O(2)saturation and heart rate for the first 24 hr after abdominal surgery. Data collection was performed from April 1 to September 30, 2006. Forty patients undergoing a gastrectomy under general anesthesia were randomly allocated to the experimental or control group. The experimental group (20 patients) was administered Morphine and Ketorolac approximately 1 hr prior to skin incision, but the control group (20 patients) was administered Morphine and Ketorolac at peritoneum closure through a patient-controlled analgesia (PCA) pump. Postoperative pain, blood pressure, heart rate, cortisol, O(2)saturation, frequency of the PCA button pressed and doses of additional analgesics were observed through post operative 24 hr. Collected data was analyzed using t-test, chi(2)test, repeated measures ANOVA, and Bonferroni methods. Postoperative pain, cortisol, the frequency of PCA button pressed, and dose of additional analgesics of the experimental group were significantly lower than the control group. There were no statistical differences in blood pressure, heart rate and O(2)saturation between the experimental group and cont...Continue Reading

References

Jun 1, 1988·Pain·P D Wall
Jul 1, 1995·British Journal of Anaesthesia·J E RogersJ O Morgan-Hughes
Mar 1, 1994·The Clinical Journal of Pain·M A AshburnN L Pace
Feb 17, 1998·Journal of Perianesthesia Nursing : Official Journal of the American Society of PeriAnesthesia Nurses·M A Fiedler
Apr 24, 1999·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·K S Filos, C E Vagianos
Oct 6, 2000·Anesthesiology·I Kissin
May 31, 2001·Anesthesiology·P H NormanR W Lindsey
Dec 11, 2003·Drugs·E Andrew OchrochAllan Gottschalk
Mar 6, 2004·Orthopaedic Nursing·Mary E HagleAngela Shippee
Sep 1, 2004·European Journal of Applied Physiology·Yoshihito KurazumiTetsumi Horikoshi
Oct 12, 2004·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·David C Randall
Apr 30, 2005·Anesthesia Progress·Eliezer KaufmanAvishag Kadari
Dec 13, 2005·Anesthesia and Analgesia·Jeffrey A Grass

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