The effects of probiotic and selenium co-supplementation on parameters of mental health, hormonal profiles, and biomarkers of inflammation and oxidative stress in women with polycystic ovary syndrome

Journal of Ovarian Research
Mehri JamilianZatollah Asemi

Abstract

The aim of this study was to evaluate the effect of the co-administration of probiotic and selenium on parameters of mental health, hormonal profiles, and biomarkers of inflammation and oxidative stress in women with PCOS. Data on the effects of selenium and probiotic co-supplementation on mental health, hormonal and inflammatory parameters of patients with polycystic ovary syndrome (PCOS) are scarce. This investigation was carried out to evaluate the effects of selenium and probiotic co-supplementation on mental health, hormonal and inflammatory parameters in women with PCOS. This randomized, double-blinded, placebo-controlled clinical trial was conducted on 60 subjects, aged 18-40 years old. Participants were randomly allocated into two groups to intake 8 × 109 CFU/day probiotic plus 200 μg/day selenium supplements (n = 30) or placebo (n = 30) for 12 weeks. Hormonal and inflammatory parameters were measured at baseline and after the 12-week intervention. Probiotic and selenium co-supplementation resulted in a significant improvement in beck depression inventory (β - 0.76; 95% CI, - 1.26, - 0.26; P = 0.003), general health questionnaire scores (β - 1.15; 95% CI, - 1.97, - 0.32; P = 0.007) and depression anxiety and stress scal...Continue Reading

References

Feb 1, 1979·Psychological Medicine·D P Goldberg, V F Hillier
Jun 1, 1961·Archives of General Psychiatry·A T BECKJ ERBAUGH
Jan 10, 2006·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Jennifer A NettletonMindy S Kurzer
Feb 25, 2006·Human Reproduction·Evanthia Diamanti-KandarakisDimitrios Panidis
May 7, 2009·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·L H Duntas
Jun 30, 2009·Wiener klinische Wochenschrift·Elisabeth WehrBarbara Obermayer-Pietsch
Dec 28, 2010·Clinical Biochemistry·Etiane TatschRafael Noal Moresco
Feb 18, 2011·The Cochrane Database of Systematic Reviews·Lisa J MoranHelena J Teede
Aug 11, 2012·The Journal of Clinical Endocrinology and Metabolism·Thozhukat SathyapalanStephen L Atkin
Mar 16, 2013·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Ayhan CoskunHasan Çetin Ekerbiçer
Jul 11, 2013·Mediators of Inflammation·Bruno Melo Carvalho, Mario Jose Abdalla Saad
Nov 22, 2013·Toxicology and Industrial Health·Magdy A Ghoneim, Said S Moselhy
Jan 1, 2013·Journal of Nutritional Science·S A MattmillerL M Sordillo
Jun 13, 2015·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Barkath Nisha Hyderali, Kanchana Mala
Jan 16, 2016·Oxidative Medicine and Cellular Longevity·Tao ZuoWenming Xu
Feb 9, 2016·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Fatemeh Mohammad HosseinzadehBatool Rashidi
Jul 19, 2016·Current Pharmaceutical Design·Basak Ozgen Saydam, Bulent O Yildiz
May 24, 2017·Nutrients·Yang WangWeifen Li
Oct 3, 2017·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·W JuX B Gao
Dec 30, 2017·Genes·Silke Crommen, Marie-Christine Simon
Mar 24, 2018·Nature Reviews. Endocrinology·Héctor F Escobar-Morreale

❮ Previous
Next ❯

Citations

Oct 30, 2018·Minerva medica·Ludovico Abenavoli, Dan L Dumitrascu
Nov 2, 2019·Biological Trace Element Research·Batool Hossein RashidiMohammad Javad Hosseinzadeh-Attar
Aug 20, 2019·Reproductive Biology and Endocrinology : RB&E·Jingshun ZhangLianwen Zheng
May 7, 2020·European Journal of Nutrition·Mauro CozzolinoNicolas Garrido
Feb 6, 2020·Frontiers in Neuroscience·Shin Jie YongWei Ling Lim
Oct 27, 2020·Current Rheumatology Reports·Marina Bañuls-MireteMonica Guma
Dec 6, 2019·Frontiers in Neuroendocrinology·Minal JaggarJohn F Cryan
Jan 8, 2021·Reproductive Sciences·Jingbo GuoJunping Hu
Jun 15, 2021·Journal of Cellular Physiology·Ling WangFenge Li
Jul 22, 2021·Critical Reviews in Food Science and Nutrition·Yuling LiJiaqi Shuai
Aug 28, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Liyun DuanFengmei Lian

❮ Previous
Next ❯

Methods Mentioned

BETA
ELISA
MDA

Software Mentioned

nutritionist IV
Statistical Package for Social Science

Related Concepts

Related Feeds

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.