The effects of prostaglandins E1, E2 and F2alpha on vagal bradycardia in the anaesthetized mouse.

British Journal of Pharmacology
W Feniuk, B J Large

Abstract

1 In anesthetized mice prostaglandins E1 and E2 reduced the bradycardia caused by electrical stimulation of the sectioned peripheral vagus nerve; prostaglandin F2alpha produced only a slight inhibition of the vagal response. 2 None of the prostaglandins studied affected acetylcholine-induced bradycardia. 3 Prostaglandins modify parasympathetic nerve activity in vivo presumably by a pre-synaptic action.

References

May 1, 1970·Acta Physiologica Scandinavica·P HedqvistA Wennmalm
Apr 15, 1971·Life Sciences. Pt. 1: Physiology and Pharmacology·A Wennmalm, P Hedqvist
Sep 1, 1973·European Journal of Pharmacology·P HadházyJ Knoll
Oct 1, 1967·The American Journal of Physiology·F CoceaniL S Wolfe

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Citations

Dec 1, 1989·Prostaglandins, Leukotrienes, and Essential Fatty Acids·R Serio, E E Daniel
Mar 22, 2002·The Journal of Pharmacology and Experimental Therapeutics·Sandrine N HardouinNeil M Nathanson
Sep 1, 1987·The Journal of Pharmacy and Pharmacology·M S YatesC J Bowmer
Jul 1, 1976·British Journal of Pharmacology·M E Chieruttini, C S Franklin
Mar 1, 1985·The Journal of Pharmacy and Pharmacology·M S YatesC J Bowmer

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