The effects of provider-prescribed obesogenic drugs on post-laparoscopic sleeve gastrectomy outcomes: a retrospective cohort study

International Journal of Obesity : Journal of the International Association for the Study of Obesity
Cecilia B LeggettAmir Zarrinpar

Abstract

Laparoscopic sleeve gastrectomy (LSG) is one of the most commonly performed bariatric procedures and has proven effective in providing weight loss. However, considerable variance has been noted in the degree of weight loss. Physician prescription practices may be negatively affecting weight loss post-LSG and, thus, contributing to the broad range of weight loss outcomes. The aim of our study was to determine whether commonly prescribed obesogenic medications negatively affect weight loss outcomes post-LSG. This single center retrospective cohort study performed at a University hospital included 323 patients (≥18 years) within the University California, San Diego Healthcare System who underwent LSG between 2007 and 2016. We identified a list of 32 commonly prescribed medications that have weight gain as a side effect. We compared the percent excess weight loss (%EWL) of patients divided into two groups based on post-LSG exposure to obesogenic medications. A linear regression model was used to analyze %EWL at 12 months post-LSG while controlling for age, initial body mass index (BMI), and use of leptogenic medications. A total of 150 patients (Meds group) were prescribed obesogenic medications within the one-year post-LSG follow ...Continue Reading

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Citations

Dec 10, 2020·JAMA Surgery·Grace F ChaoAmir A Ghaferi
Jul 14, 2020·Journal of the American Association of Nurse Practitioners·Frances M Sahebzamani

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