The effects of refeeding on peripheral and respiratory muscle function in malnourished chronic obstructive pulmonary disease patients

The American Review of Respiratory Disease
J S WhittakerJ D Road

Abstract

We carried out a prospective randomized controlled trial to investigate the effects of short-term refeeding (16 days) in 10 malnourished inpatients with chronic obstructive pulmonary disease (COPD). Six patients were randomized to receive sufficient nasoenterically administered calories to provide a total caloric intake equal to 1,000 kcal above their usual intake. The other four patients were sham fed, receiving only 100 kcal more. Measurements of nutritional status, respiratory muscle strength and endurance, adductor pollicis function, and pulmonary function were performed initially and at study end. The refed group gained significantly more weight and showed significant increases in maximal expiratory pressure and mean sustained inspiratory pressure. There were no significant changes in the maximal inspiratory pressure or in adductor pollicis function. In malnourished inpatients with COPD, short-term refeeding leads to improvement in respiratory muscle endurance and in some parameters of respiratory muscle strength in the absence of demonstrable changes in peripheral muscle function.

References

Aug 1, 1978·Thorax·W M Thurlbeck
Jan 1, 1989·The American Review of Respiratory Disease·G McElvaneyR L Pardy
Jan 1, 1983·Journal of the American College of Nutrition·M DeitelT W Rice
Jan 1, 1983·The American Journal of Clinical Nutrition·D M RussellK N Jeejeebhoy
Aug 1, 1983·The American Journal of Clinical Nutrition·D M RussellK N Jeejeebhoy
Jan 1, 1982·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·N S Arora, D F Rochester

❮ Previous
Next ❯

Citations

Feb 16, 2002·Journal of the American Dietetic Association·Inga Thorsdottir, Ingibjorg Gunnarsdottir
Jul 1, 1996·The American Journal of Medicine·W ChatilaC A Manthous
Jun 1, 1997·Disease-a-month : DM·B A Mizock, S Troglia
Apr 7, 2000·Molecular Aspects of Medicine·J MercierR Ventura
Aug 31, 1999·The Proceedings of the Nutrition Society·J Congleton
Mar 17, 2004·The Proceedings of the Nutrition Society·Annemie Schols
Mar 31, 2000·Current Opinion in Pulmonary Medicine·A M Schols
Feb 27, 2001·Current Opinion in Pulmonary Medicine·N J Gross
Jan 11, 2000·Current Opinion in Clinical Nutrition and Metabolic Care·J M Potter
Jun 11, 2008·Current Opinion in Clinical Nutrition and Metabolic Care·Wahju AniwidyaningsihChristophe Pison
Aug 26, 1998·BMJ : British Medical Journal·J PotterM Roberts
Oct 6, 1997·American Journal of Respiratory and Critical Care Medicine·H Saudny-UnterbergerK Gray-Donald
Jun 25, 1998·American Journal of Respiratory and Critical Care Medicine·A M ScholsE F Wouters
Jan 5, 1999·American Journal of Respiratory and Critical Care Medicine
Dec 10, 1999·American Journal of Respiratory and Critical Care Medicine·C LandboT P Almdal
Mar 11, 2000·American Journal of Respiratory and Critical Care Medicine·H Sahebjami, E Sathianpitayakul
Jun 9, 2006·American Journal of Respiratory and Critical Care Medicine·Linda NiciUNKNOWN ATS/ERS Pulmonary Rehabilitation Writing Committee
Jan 24, 2002·American Journal of Respiratory Cell and Molecular Biology·Stefan MateckiMichele Ramonatxo
Dec 1, 2007·International Journal of Chronic Obstructive Pulmonary Disease·Hope E UronisAmy P Abernethy
Dec 11, 2002·Journal of General Internal Medicine·Dennis H SullivanPaula K Roberson
Oct 1, 1992·Chest·C F RyanJ D Road
Jun 3, 2008·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·S ViolaJ-P Girardet
Oct 31, 2007·Clinics in Chest Medicine·Shoab A NazirMarcia L Erbland
May 24, 2007·Archivos de bronconeumología·Sergio Alcolea BatresRodolfo Alvarez-Sala
Feb 26, 2013·Respirology : Official Journal of the Asian Pacific Society of Respirology·Peter F CollinsRebecca J Stratton
Jun 15, 2015·Archivos de bronconeumología·Esther BarreiroJosé Miguel Rodríguez-González Moro
Feb 24, 2001·Clinics in Chest Medicine·F MaltaisR Casaburi
Aug 13, 2002·Hematology/oncology Clinics of North America·Deborah J Dudgeon
Jul 17, 2001·Respiratory Medicine·N Ambrosino, G Scano
May 1, 1997·Respiratory Medicine·C Thomsen
Oct 13, 2005·Respiratory Medicine·Marc DecramerStefano Marinari
Oct 1, 1996·Respiratory Medicine·H F van der HeijdenC L van Herwaarden
Dec 11, 2013·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Anneli ReevesMichelle Palmer
Oct 11, 2005·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Antara Mallampalli
Feb 24, 2001·Clinics in Chest Medicine·A M Schols, E F Wouters
Nov 11, 2005·Chronic Respiratory Disease·J P Fuld, M M Cotton
Aug 31, 2010·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·UNKNOWN National Alliance for Infusion Therapy and the American Society for Parenteral and Enteral Nutrition Public Policy Committee
Dec 1, 2017·Critical Care : the Official Journal of the Critical Care Forum·Nicolas TerziUNKNOWN OUTCOMEREA study group

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.