The Effects of Remifentanil on Hemodynamic Response Attenuation After Electroconvulsive Therapy Under Sevoflurane Anesthesia

The Journal of ECT
Feray ErdilMahmut Durmus

Abstract

We evaluated the effects of a single loading dose of remifentanil (1 μg/kg) administered as an adjunct to sevoflurane, on the duration of seizure activity, recovery times, and hemodynamic profiles, during electroconvulsive therapy. The patients were randomly allocated to receive sevoflurane-saline (Group SS) or sevoflurane-remifentanil (Group SR). Sevoflurane (8%) was initiated for anesthesia induction in both groups until loss of consciousness was achieved. Remifentanil was then administered to Group SR via a 1-μg/kg intravenous bolus. Patients in Group SS received saline in the same manner. Mean arterial pressure (MAP) and heart rate (HR) were recorded before anesthetic induction (T1), at the loss of consciousness (T2), and at 0, 1, 3, and 10 minutes after the electrical stimuli were completed (T3, T4, T5, and T6, respectively). Compared with the baseline values, HR increased significantly in Group SS at times T2 and T4 to T6 and decreased significantly in Group SR at time T2. When the groups were compared, we found that HR decreased significantly in Group SR at T2 and T4 to T6. Compared with baseline, MAP increased in Group SS between T3 and T6, and MAP decreased in Group SR at T2 and increased at T3 to T4. Mean arterial pre...Continue Reading

References

Nov 1, 1978·Comprehensive Psychiatry·B M Maletzky
Mar 1, 1991·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·A L KovacK Arakawa
Aug 14, 1998·Journal of Clinical Anesthesia·M N AvramovM M Husain
Jul 27, 2001·Acta Anaesthesiologica Scandinavica·F A AndersenH Holst-Larsen
Feb 22, 2005·Journal of Clinical Anesthesia·Georgia KostopanagiotouGeorge Kottis
Nov 23, 2005·The Journal of ECT·Keith G RasmussenW Michael Hooten
Jun 16, 2011·The Journal of ECT·Stephen T Chen

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Citations

Jun 6, 2018·Current Opinion in Anaesthesiology·Pavan Kumar Kadiyala, Lakshmi Deepthi Kadiyala
Jul 12, 2018·Current Opinion in Anaesthesiology·Martin Soehle, Janina Bochem
Jun 26, 2021·Journal of Psychiatric Research·Nobuatsu AokiYoshiteru Takekita

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