PMID: 43800Jan 1, 1979

The effects of rubidium on mammary tumour growth in C57 blk/6J mice

Cytobios
A K BrewerN Rothkopf

Abstract

A high pH therapy for cancer arrived at theoretically was tested in mice by feeding them rubidium carbonate. Tumours were transplanted in the abdomen of mice and allowed to grow for 8 days. The mice were then divided into two groups. The control group was continued on conventional mouse chow. The test group, in addition to the mouse chow, was force-fed 1.11 mg of rubidium carbonate dissolved in distilled water. At the end of 13 more days the tumours in the controls had grown to a large size so all the mice were sacrificed. The tumours were then removed and weighed. The tumours in the test animals weighed essentially one eleventh of those in the controls. In addition the test animals were showing no adverse effects from the cancers. The probability that this marked difference in tumour size could have come about by chance is exceedingly small.

Related Concepts

Hydrogen-Ion Concentration
Kidney
Mammary Neoplasms, Experimental
Mice, Inbred Strains
Rubidium

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