PMID: 9533633Apr 9, 1998Paper

The effects of SchistoFLRFamide on contractions of locust midgut

Peptides
A B Lange, I Orchard

Abstract

The midgut of insects has recently been shown to contain numerous endocrine-like cells and the midgut is now considered one of the largest endocrine organs in the insect. Using immunohistochemistry, radioimmunoassay, and muscle bioassay techniques, the midgut of the adult locust, Locusta migratoria, has been investigated for the distribution and possible function of FMRFamide-related peptides contained within these endocrine-like cells and innervation. Endocrine-like cells containing RFamide-like immunoreactivity were observed to be unequally distributed throughout the midgut. RFamide-like immunoreactivity was also seen in the ingluvial ganglion and in the nerves projecting posteriorly to the midgut. These axonal tracts resulted in extensive arborizations over the posterior midgut which were RFamide-like immunoreactive. Radioimmunoassay indicated larger amounts of FMRFamide equivalents in female locust midgut as compared to males with an unequal distribution of FMRFamide-like immunoreactivity in the gastric caeca and in the anterior and posterior parts of the midgut. Circular muscle contraction of the midgut was monitored using a ring-type preparation. Structure/activity studies have shown that the only FMRFamide-related peptid...Continue Reading

References

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Citations

Jan 26, 2002·Microscopy Research and Technique·Uwe Homberg
Aug 9, 2003·Proceedings of the National Academy of Sciences of the United States of America·Kristoffer EgerodCornelis J P Grimmelikhuijzen
Jan 6, 2016·Archives of Insect Biochemistry and Physiology·Magdalena Bil, Roger Huybrechts
Feb 21, 2016·Peptides·Ladislav RollerDušan Žitňan
May 11, 2010·Journal of Insect Physiology·Lisa Robertson, Angela B Lange
Dec 17, 2009·General and Comparative Endocrinology·Volker HartensteinKatrina L Adams
Dec 13, 2006·Peptides·Jacqueline C BedeStephen S Tobe
Jan 5, 2005·Biochemical and Biophysical Research Communications·Susanne SchöllerCornelis J P Grimmelikhuijzen
Sep 4, 2010·Journal of Insect Physiology·Paul D Cooper, Nancy E Beckage
Oct 31, 2015·Scientific Reports·Raquel S M GodoyGustavo F Martins
Jul 20, 2001·Archives of Insect Biochemistry and Physiology·S M Rankin, S M Seymour
Sep 24, 2004·The Journal of Biological Chemistry·Kyu-Sun LeeKweon Yu
Feb 11, 2005·The Journal of Biological Chemistry·Naoki YamanakaHiroshi Kataoka
May 25, 2012·The Journal of Experimental Biology·Dohee LeeAngela B Lange
Jun 14, 2012·The Journal of Experimental Biology·Lisa RobertsonAngela B Lange

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