The Effects of Sex and Pubertal Maturation on Cardiovagal Baroreflex Sensitivity

The Journal of Pediatrics
Daniele ChiricoDeborah D O'Leary

Abstract

To examine baroreflex sensitivity (BRS) across different stages of pubertal maturation in healthy children and adolescents. This study was cross-sectional and included 104 participants (53 males and 51 females) aged 8-18 years old. Participants were organized into 5 pubertal groups based on the criteria of Tanner; prepubertal (Tanner 1, n = 19), early-pubertal (Tanner 2, n = 16), peripubertal (Tanner 3, n = 24), late-pubertal (Tanner 4, n = 23), and postpubertal (Tanner 5 and 6, n = 22). Adiposity (fat-free mass, fat mass, and body fat%), body mass index, and demographic variables were collected. Beat-by-beat blood pressure and R-R interval were collected during supine rest to determine BRS. BRS was assessed by transfer function analysis in the low frequency range (0.05-0.15 Hz). The results demonstrated a sex-by-maturation interaction [F(4, 94) = 3.202, P = .019]. BRS decreased from early-to postpuberty in males (30 [7.1] vs 13.2 [7.8] ms/mm Hg), and remained unchanged in females. This led to significantly greater BRS in females compared with males, postpuberty (27 [7.3] vs 13.2 [7.8] ms/mm Hg). Controlling for both sex and maturation when examining BRS in children and adolescents with cardiovascular disease risk factors will ...Continue Reading

References

Jul 1, 1986·Acta paediatrica Scandinavica·E VartiainenA Nissinen
Feb 1, 1970·Archives of Disease in Childhood·W A Marshall, J M Tanner
Jun 1, 1969·Archives of Disease in Childhood·W A Marshall, J M Tanner
Oct 31, 1998·Canadian Journal of Physiology and Pharmacology·M M el-Mas, A A Abdel-Rahman
Mar 10, 2001·Paediatric and Perinatal Epidemiology·S J TaylorD G Cook
May 23, 2002·Journal of Hypertension·Lilian KornetRobert S Reneman
Jul 26, 2003·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Makoto TanakaToshiaki Nishikawa
Nov 7, 2003·The Journal of Clinical Endocrinology and Metabolism·Anna A AhimastosBronwyn A Kingwell
Oct 13, 2004·Circulation·Zsuzsanna LenardMark Kollai
Oct 29, 2004·The Journal of Clinical Endocrinology and Metabolism·R Ravi ShankarJ Howard Pratt
Mar 2, 2006·Journal of Hypertension·Andrea DietrichJudith G M Rosmalen
May 10, 2007·Canadian Journal of Physiology and Pharmacology·Eva ZavodnaBohumil Fiser
Apr 23, 2008·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Maria Teresa La RovereGrzegorz Raczak
Jul 18, 2008·JAMA : the Journal of the American Medical Association·Philip R NaderMarion O'Brien
Dec 23, 2009·Molecular and Cellular Endocrinology·Juan RoaManuel Tena-Sempere
Jun 18, 2010·Biological Psychology·Andrea DietrichHarriëtte Riese
Nov 3, 2010·Research in Developmental Disabilities·Daniele ChiricoBrent Faught
Feb 15, 2011·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Peter L LatchmanRonald E De Meersman
Mar 24, 2012·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Laura K FitzgibbonDeborah D O'Leary
Sep 20, 2012·European Journal of Endocrinology·Manuel Tena-Sempere
Apr 12, 2013·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Christopher E SchwartzJulian M Stewart
Apr 16, 2013·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Agnieszka RydlewskaEwa A Jankowska
Aug 24, 2013·The Journal of Pediatrics·Kara L MarlattAaron S Kelly
Jan 31, 2014·Muscle & Nerve·Naoki WadaPhillip A Low

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Citations

Apr 25, 2016·Child Abuse & Neglect·Stephen A KlassenTerrance J Wade
Oct 17, 2017·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·L H P M FilippiniA A M Wilde
Feb 24, 2018·Clinical Physiology and Functional Imaging·Ricardo S OliveiraCraig A Williams
Feb 8, 2019·European Journal of Applied Physiology·Ricardo S OliveiraCraig A Williams

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