The effects of supportive care interventions on depressive symptoms among patients with lung cancer: A metaanalysis of randomized controlled studies

Palliative & Supportive Care
Chia-Chen Hsieh, Fei-Hsiu Hsiao

Abstract

Our aim was to examine the effect of supportive care interventions on depressive symptoms in patients with lung cancer. We searched the databases of the Cochrane Central Register of Controlled Trials (CENTRAL), Ovid EMBASE, PubMed, and the Chinese Electronic Periodical Services (CEPS) from their inception until September of 2015. We included randomized controlled trial studies that compared standard care with supportive care interventions. The standardized mean difference (SMD) (Cohen's d) was calculated to estimate the effect of interventions. Subgroup analysis was conducted to identify possible sources of heterogeneity. A total of 1,472 patients with lung cancer were identified. Compared with standard care, the overall effects of all supportive care interventions significantly reduced depressive symptoms (SMD = -0.74, CI 95% = -1.07 to -0.41), and the effects could be maintained at weeks 4, 8, and 12 of follow-up. Three types of supportive care interventions were identified: psychotherapy combined with psychoeducation, psychoeducation alone, and an exercise program. Both psychotherapy combined with psychoeducation and exercise significantly improved depressive symptoms, while psychoeducation alone did not yield significant ef...Continue Reading

References

Jul 2, 2003·Cancer Nursing·Sally L MaliskiGeraldine Padilla
Jul 30, 2008·Palliative & Supportive Care·Penelope SchofieldSanchia Aranda
Jul 28, 2009·Journal of Clinical Epidemiology·David MoherUNKNOWN PRISMA Group
Sep 14, 2010·Journal of Pain and Symptom Management·Laura S PorterCindy Scipio
Oct 14, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Linda E CarlsonBarry D Bultz
Oct 16, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Yu-Chien LiaoYeur-Hur Lai
Feb 8, 2011·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Konstantinos D StathopoulosGrigorios Skarantavos
Mar 23, 2011·The Surgical Clinics of North America·Betty FerrellAnnie Harrington
Nov 10, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Lynette L CraftKerry S Courneya
Mar 3, 2012·Psycho-oncology·Brian D Gonzalez, Paul B Jacobsen
Mar 21, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·William F PirlJennifer S Temel
Jun 26, 2012·Journal of Affective Disorders·Wolfgang LindenDuncan Greig
Oct 30, 2012·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Jane WalkerMichael Sharpe
Dec 19, 2012·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·Roma MaguireLynn Irvine
Jan 16, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Hermann FallerRoland Küffner
Jun 19, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Allison W BoyesMariko L Carey
Oct 2, 2013·Clinical Oncology : a Journal of the Royal College of Radiologists·D R SullivanC G Slatore
Oct 5, 2013·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Jin Sheng Hong, Jun Tian
Mar 19, 2014·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·Rebecca H Lehto
Apr 16, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Barbara L AndersenUNKNOWN American Society of Clinical Oncology
Jun 13, 2014·OncoTargets and Therapy·Benchalak ManeetonSumitra Thongprasert
Oct 9, 2014·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Markus W HaunMechthild Hartmann
Oct 11, 2014·Current Oncology·D DirkseJ Giese-Davis
Oct 18, 2014·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Alex MolassiotisMeinir Krishnasamy
Nov 25, 2014·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·A MolassiotisY Summers
Apr 2, 2015·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Brett C BadeGerard A Silvestri
Jul 15, 2015·Journal of Pain and Symptom Management·Joseph A GreerJennifer S Temel
Sep 12, 2015·Journal of the National Comprehensive Cancer Network : JNCCN·Namrata VijayvergiaCrystal S Denlinger
Sep 28, 2015·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Samina ParkYoung Tae Kim
Oct 9, 2015·Asian Journal of Sports Medicine·Elaheh RanjbarMohammad Ali Eshghi

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Citations

Oct 30, 2020·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·Svetlana V Doubova, Ricardo Pérez-Cuevas
Oct 17, 2020·Clinical Lung Cancer·Mick van de WielAnnelies Janssens

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