PMID: 9641528Jun 26, 1998Paper

The effects of TGF-beta1 on chick embryo retina development in vitro

International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience
G CalvarusoG Tesoriere

Abstract

This paper studies the effect exerted by TGF-beta1 on the development of chick embryo retina cultured in vitro. The addition of TGF-beta1 to retinal explants inhibited DNA synthesis, measured as 3H-thymidine incorporation into trichloroacetic acid-insoluble fraction, while it increased both wet weight and protein content, in particular that of extracellular matrix proteins. Lastly, in explants treated with TGF-beta1 an increment in the level of fibronectin was demonstrated by means of Western blotting analysis.

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Citations

Jun 16, 2007·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Guilherme Rapozeiro FrançaAna Lucia Marques Ventura

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