PMID: 8964776Apr 1, 1996Paper

The effects of time-varying curvature on velocity profiles in a model of the coronary arteries

Journal of Biomechanics
S SchiltJ J Meister

Abstract

Blood flow patterns in the coronary arteries are of interest due to their possible involvement in atherosclerosis localization. Spatial variations in hemodynamic flow patterns are predominantly determined by the vessel geometry. The coronary arteries represent a unique situation in the cardiovascular system because their geometry undergoes large dynamic variations during each cardiac cycle due to the contraction of the heart. This study was initiated to analyze the effects of time-varying curvature on flow velocity profiles in a curved tube model of the coronary arteries. An in vitro flow model was constructed, which consisted of a flexible curved tube through which fluid flowed under a steady imposed pressure gradient. The radius of curvature of the tube was varied in time using a stepper motor and carriage. Two different deformation configurations were used to determine if variations in center of curvature displacement affected the velocity profiles. It was found in both cases that the skewing of the axial velocity profile depended on the instantaneous dynamic vessel movement, with maximal skewing occurring when the radius of curvature was in transition from the minimum to the maximum value. The change in skewing was greater ...Continue Reading

References

Mar 1, 1992·Journal of Biomechanics·Y C PaoE L Ritman
May 1, 1985·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·D N KuS Glagov

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Citations

Feb 26, 2008·Biomechanics and Modeling in Mechanobiology·J Scott VanEppsDavid A Vorp
Jan 29, 2005·Annals of Biomedical Engineering·S D RamaswamyK B Chandran
Oct 20, 2006·Annals of Biomedical Engineering·Maheshwaran K KolandavelPeter G Walker
Aug 17, 2001·Journal of Biomechanics·E S Weydahl, J E Moore
Sep 4, 1998·Journal of Biomechanics·M F Gross, M H Friedman
May 9, 2001·Journal of Biomechanical Engineering·J E MooreA Santamarina
Mar 15, 2006·Journal of Biomechanical Engineering·S D RamaswamyK B Chandran
Sep 25, 2004·Journal of Biomechanics·Martin ProsiMorton H Friedman
Dec 23, 2008·The Annals of Thoracic Surgery·Lindsay C H John
Apr 8, 2016·Computer Methods in Biomechanics and Biomedical Engineering·Kalimuthu GovindarajuAbdullah A A A Al-Rashed
Sep 7, 2013·Journal of Biomechanical Engineering·Mahmudul HasanWei Yin
Jul 24, 1998·Journal of Biomechanical Engineering·M R MorenoR Meuli

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