PMID: 6411322Oct 1, 1983Paper

The effects of total-body hyperthermia combined with anticancer drugs on immunity in advanced cancer patients

Cancer
S KogaH Kanayama

Abstract

As total-body hyperthermia (TBHT) therapy may lead to a reduction in the immune response of cancer patients because of the immediate effect of heat on lymphocytes, the authors studied the immunity of advanced cancer patients receiving combined TBHT and anticancer chemotherapy. A decrease was found in their lymphocyte blastogenesis, skin reactions to PPD and PHA, lymphocyte rosette formation, IgG, and C3c component. These parameters returned to their pretreatment levels at 1 week after completion of TBHT therapy. This result indicates that there is no necessity for giving special consideration to a reduction of cell-mediated immunity in TBHT therapy.

References

Apr 1, 1977·Journal of the National Cancer Institute·R J DeHoratiusR C Williams
Jun 1, 1976·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·A Yerushalmi

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Citations

Jan 1, 1990·The Japanese Journal of Surgery·H YoshiokaA Murakami
Jan 1, 1989·Pharmacology & Therapeutics·J L MeyerG H Hahn
Jun 25, 2013·Journal of Biotechnology·Teruya EnomotoHiroshi Handa
Oct 3, 1999·Veterinary Immunology and Immunopathology·M J OglesbeeS Krakowka
Apr 1, 1996·International Journal of Radiation Oncology, Biology, Physics·D S Kapp
Jan 1, 1995·Cancer Biotherapy·L M Shecterle, J A St Cyr
Mar 1, 1990·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·A YoshiokaM Abe
Mar 1, 1991·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·R HamazoeN Kaibara
Mar 1, 1992·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·E H GreeleyM Segre

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