The Effects of Volume-Controlled and Pressure-Controlled Ventilation on Lung Mechanics, Oxidative Stress, and Recovery in Gynecologic Laparoscopic Surgery

Journal of Minimally Invasive Gynecology
Chia-Chih LiaoChin-Jung Wang

Abstract

To compare ventilation variables, changes in oxidative stress, and the quality of recovery in 2 different ventilation strategies (volume-controlled ventilation [VCV] and pressure-controlled ventilation [PCV]) during gynecologic laparoscopic surgery. A prospective randomized controlled trial (Canadian Task Force classification I). One university teaching hospital in Taiwan. Women scheduled for laparoscopic gynecologic surgery. Women were randomly assigned to receive either VCV or PCV during surgery. Ventilation variables were recorded 1 minute before and 1 hour after pneumoperitoneum. Blood samples were collected for malondialdehyde measurement at 7 points: 1 minute before and 1 hour after pneumoperitoneum; 30, 60, 90, and 120 minutes after deflation; and 24 hours after surgery. Postoperative recovery was assessed by using a 9-item quality of recovery score at 24 hours after surgery. A total of 52 women randomly allocated to the VCV (n = 27) or PCV (n = 25) group completed the study. We found that after 1 hour of insufflation the PCV group had lower peak airway pressure (22.0 ± 3.4 vs 26.6 ± 4.1 cm H2O, p < .0001) and higher compliance (28.4 ± 3.7 vs 24.1 ± 3.3 mL/cm H2O, p < .0001) than the VCV group. In plasma levels of malond...Continue Reading

Associated Clinical Trials

Sep 25, 2018·Hakan Yılmaz

References

Mar 1, 1996·Surgical Endoscopy·E EleftheriadisJ Dadoukis
Aug 12, 2000·Acta Anaesthesiologica Scandinavica·A M Koivusalo, L Lindgren
Feb 25, 2003·American Journal of Respiratory and Critical Care Medicine·Cyrus EdibamAndrew D Bersten
Jan 24, 2004·The Tohoku Journal of Experimental Medicine·M Hakan BukanTurgut Tufan
Aug 9, 2005·Free Radical Biology & Medicine·Gwen KennedyJill J F Belch
Aug 17, 2005·Current Pharmaceutical Design·Young-Ger Suh, Uhtaek Oh
Oct 29, 2005·The Journal of Physiology·Philip I AaronsonJeremy P T Ward
Mar 21, 2007·Critical Care Clinics·Dane Nichols, Sai Haranath
Nov 27, 2007·Free Radical Biology & Medicine·Chutima MatayatsukBarry Halliwell
Dec 20, 2007·Current Opinion in Clinical Nutrition and Metabolic Care·Tilman Grune, Mette M Berger
Jul 11, 2009·The British Journal of Surgery·T SammourA G Hill
Mar 23, 2010·Journal of Minimally Invasive Gynecology·Mustafa OğurluAhmet Coşar
Jul 7, 2011·Acta Anaesthesiologica Taiwanica : Official Journal of the Taiwan Society of Anesthesiologists·Chiao-Fen LuoHuang-Ping Yu

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Citations

Mar 22, 2016·Journal of Minimally Invasive Gynecology·Ospan A MynbaevAndrea Tinelli
Mar 22, 2016·Journal of Minimally Invasive Gynecology·Chia-Chih LiaoChin-Jung Wang
Apr 13, 2018·Minerva anestesiologica·Antonio CorcioneUNKNOWN Società Italiana di Anestesia Analgesia Rianimazione e Terapia Intensiva (SIAARTI) and Società Italiana di Chirurgia (SIC)
Nov 18, 2020·Respiratory Physiology & Neurobiology·Matheus Rocha AlmeidaFrank Silva Bezerra

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