The efficacy and prescription of neuromuscular electrical stimulation (NMES) in adult cancer survivors: a systematic review and meta-analysis

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
Dominic O'ConnorOlive Lennon

Abstract

This study aims to (1) summarise and critically evaluate the effects of neuromuscular electrical stimulation (NMES) on indices of health and quality of life (QoL) in adult cancer survivors, (2) assess the safety of NMES as a rehabilitation method in this population, and (3) identify commonly used NMES treatment parameters and describe treatment progression. A systematic search of four electronic databases targeted studies evaluating the effects of NMES on physical function, aerobic fitness, muscle strength, body composition, and health-related quality of life (HR-QoL) in adult cancer survivors, published through March 2018. Two reviewers independently reviewed and appraised the risk of bias of each study. Nine studies were included. Meta-analyses found that the overall pooled effect favoured NMES for improving muscle strength, but the standardised mean difference was not significant (0.36; 95% CI - 0.25, 0.96). Further meta-analyses indicated that NMES significantly improved HR-QoL (0.36; 95% CI 0.10, 0.62), with notable gains identified under the subcategories QoL Function (0.87; 95% CI 0.32, 1.42). Current NMES prescription is not standardised and NMES is prescribed to target secondary complications of treatment. Risk of bias...Continue Reading

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Citations

Oct 31, 2019·Journal of Medical Internet Research·Gabriel Ruiz SignorelliJuan M Garcia-Gomez
Feb 9, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Dominic O'ConnorBrian Caulfield
Mar 18, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Dominic O'ConnorBrian Caulfield
Mar 19, 2021·Medicine and Science in Sports and Exercise·Camila S PadilhaRafael Deminice
Nov 21, 2021·Scientific Reports·Nicholas FritzJennifer M Blain Christen

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