The efficacy, applicability and side-effects of postoperative intravenous patient-controlled morphine analgesia: an audit of 1233 Chinese patients

Anaesthesia and Intensive Care
S L TsuiJ Yang

Abstract

We analyzed data from 1233 Chinese patients of a wide age range who received patient-controlled analgesia (PCA) intravenous morphine for postoperative pain relief, during the period of January 1992 to May 1995. The analgesic regimen was standardized as follows: PCA bolus 1 to 1.5 mg; lock-out interval 5 minutes; one-hour maximum dose 0.075 to 0.1 mg.kg-1 and background infusion 0 or 0.5 mg.h-1. Most patients underwent major surgery that was broadly subclassified according to the anatomical area involved. The median verbal numerical rating scales of pain (0 to 10) at rest and while coughing for the first, second and third 24 hours were 3.0/5.0, 1.5/4.0 and 0/3.0 respectively and the corresponding demand to delivery ratios were 2.8 +/- 2.9, 2.6 +/- 2.4 and 2.4 +/- 2.6. The overall morphine consumptions in 1004 of these Chinese patients were 27.5 +/- 16.8, 17.8 +/- 16.1 and 18.1 +/- 21.0 micrograms.kg-1.h-1 during the first 16, 17 to 41 and 42 to 66 postoperative hours respectively. These figures were the same as for Caucasian patients managed in the same institution. Morphine consumption was significant higher following thoracic, upper abdominal and spinal surgery. Also it was higher in patients younger than 65 years, males, ciga...Continue Reading

References

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Citations

Jan 13, 2000·Anaesthesia and Intensive Care·G A Turner, R Halliwell
Jun 8, 2010·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Daihua YuLinong Yao
Nov 3, 1998·Anaesthesia·P P ChenT E Oh
Mar 28, 2008·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Lucia GaglieseVincent W S Chan
Dec 19, 2014·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Senthilkumar SadhasivamLisa J Martin
Mar 22, 2003·Acta Anaesthesiologica Scandinavica·H PleymO Dale
Aug 27, 2005·Neurosurgical Focus·W Scott JellishJohn P Leonetti
Feb 22, 2008·The Clinical Journal of Pain·Polly E BijurE John Gallagher
Aug 8, 2006·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·W Scott JellishThomas C Origitano
Mar 27, 2020·Korean journal of anesthesiology·Seok-Jin Lee, Tae-Yun Sung
Sep 14, 2010·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Salah Sakka, Christian Krenkel

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