The Efficacy of Deep Sclerectomy on Posture-induced Intraocular Pressure Changes

Journal of Glaucoma
Vittoria AragnoPascale Hamard

Abstract

The purpose of this study was to evaluate the efficacy of nonpenetrating deep sclerectomy (NPDS) on posture-induced intraocular pressure (IOP) changes in open-angle glaucoma (OAG). Twenty-five eyes of 25 patients with OAG that underwent NPDS were included in this study. IOP was measured with the IcarePro (ICP) tonometer in the sitting, supine, dependent lateral decubitus position (DLDP), and nondependent lateral decubitus position (NDLDP) before surgery, and at 1 and 3 months after surgery. The mean baseline IOP measured in the sitting position was 20.5±8.4 mm Hg with Goldmann applanation tonometry and 19.6±6.5 mm Hg with ICP. At 1 and 3 months after NPDS, mean IOP decreased significantly in each position (P<0.001). At each time point, mean IOP was higher in all lying positions than in the sitting position (P<0.001) and higher in the DLDP than in the supine and NDLDP positions (P<0.001 and P=0.001). Posture-induced IOP changes between the sitting and supine position, DLDP, and NDLDP, respectively, were significantly reduced by 77% (P=0.009), 60% (P=0.001), and 82% (P=0.01) at 1 month and by 79% (P=0.004), 70% (P<0.001), and 79% (P<0.001) at 3 months after surgery. The IOP fluctuation reduction was significantly inferior when co...Continue Reading

References

Jan 1, 1975·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·G Krieglstein, M E Langham
Nov 1, 1991·The British Journal of Ophthalmology·S YamabayashiS Tsukahara
Jul 1, 1987·The British Journal of Ophthalmology·J ParsleyA R Elkington
Nov 1, 1980·The British Journal of Ophthalmology·B I WilliamsE Letley
Mar 1, 1995·Archives of Ophthalmology·L I LarssonR F Brubaker
Jan 1, 1996·Documenta Ophthalmologica. Advances in Ophthalmology·A Kontiola
Sep 8, 2004·Ophthalmology·Kouros Nouri-MahdaviUNKNOWN Advanced Glaucoma Intervention Study
Jul 20, 2010·Survey of Ophthalmology·Tiago Santos PrataAugusto Paranhos
Aug 28, 2010·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Jennifer S WeizerSayoko E Moroi
Aug 2, 2011·Acta Ophthalmologica·Jong Yeon LeeYong Yeon Kim
Sep 14, 2011·Archives of Ophthalmology·Shan FanCarol B Toris
Feb 11, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Akira Sawada, Tetsuya Yamamoto
Feb 22, 2012·Ophthalmology·Mehrdad Malihi, Arthur J Sit
Nov 1, 2012·American Journal of Ophthalmology·Jong Yeon LeeYong Yeon Kim

❮ Previous
Next ❯

Citations

Mar 27, 2019·The British Journal of Ophthalmology·Yong Woo Kim, Ki Ho Park
Oct 8, 2019·Current Opinion in Ophthalmology·Kevin KaplowitzRobert Honkanen
Feb 24, 2021·Investigative Ophthalmology & Visual Science·Yun HsiaJehn-Yu Huang
Jun 21, 2020·Progress in Retinal and Eye Research·Gordana Sunaric Megevand, Alain M Bron

❮ Previous
Next ❯

Software Mentioned

GAT
Humphrey Field Analyzer
IcarePro
SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.