The efficacy of exercise training in kidney transplant recipients: a meta-analysis and systematic review

Clinical and Experimental Nephrology
Hideyo OguchiTadashi Sofue

Abstract

The effectiveness of exercise in kidney transplant recipients is not well established. We, therefore, performed a systematic review of the effects of exercise training in kidney transplantation recipients. We searched two electronic databases for articles up to April 2017. Inclusion criteria were as follows: randomized controlled trial and kidney transplant recipients aged 18 years or older. The main outcomes were allograft function (estimated glomerular filtration rate, eGFR), exercise tolerance (VO2 peak), and quality of life (QOL). After screening of 1303 references in PubMed and Ichushi, six randomized control trials were analyzed. For kidney transplant recipients, supervised exercise training was shown to significantly improve VO2 peak [mean difference 2.42; 95% confidence interval (95%CI) 0.22-4.63] and QOL (mean difference 7.23; 95%CI 0.94-13.52). However, exercise training did not improve allograft kidney function (mean difference 6.22; 95%CI - 13.00 to 25.44). No reporting bias was observed in any of the outcomes. There were no reports including patient survival rates and the harm associated with exercise training. Exercise training for kidney transplant recipients significantly improved exercise tolerability and QOL, ...Continue Reading

References

Oct 1, 1993·Transplantation·C P JohnsonM B Adams
Feb 24, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·H NielensE Goffin
Jul 23, 2002·Transplantation·Patricia Lynn PainterNancy L Ascher
Oct 9, 2003·Kidney International·Shunichi FukuharaUNKNOWN Worldwide Dialysis Outcomes and Practice Patterns Study
Sep 16, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Herwig-Ulf Meier-KriescheBruce Kaplan
Nov 24, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·D DuclouxJ-M Chalopin
Mar 1, 2006·Transplantation Proceedings·J JuskowaJ Sierdziński
Jun 23, 2009·Transplantation·Lucas E NikkelNasrollah Ghahramani
Aug 28, 2010·Kidney International. Supplement·David Goldsmith, Carolynn E Pietrangeli
Sep 28, 2010·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Patricia PainterKirsten L Johansen
Nov 7, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Evangelia KouidiAsterios Deligiannis
Jun 29, 2013·The International Journal of Biochemistry & Cell Biology·O SchakmanJ P Thissen
Apr 29, 2014·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Kenneth James RiessSita Gourishankar
Sep 23, 2014·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Sharlene A GreenwoodHugh S Cairns
Nov 11, 2014·Annals of Transplantation : Quarterly of the Polish Transplantation Society·Lukasz CzyżewskiAndrzej Kurowski
Dec 17, 2014·Transplantation Proceedings·I TzvetanovE Benedetti
Jul 26, 2015·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Sharlene A GreenwoodIain C Macdougall
Jan 7, 2017·World Journal of Transplantation·Tania Janaudis-FerreiraCecile Beaurepaire
Mar 30, 2017·Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia·Maryam HamiM J Mojahedi
Feb 28, 2018·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Ashley TakahashiAndrew Bostom

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Citations

Dec 2, 2020·Renal Failure·Lucia MasieroGiovanni Mosconi
Feb 21, 2021·Transplant International : Official Journal of the European Society for Organ Transplantation·Tania Janaudis-FerreiraJill Boruff
May 18, 2021·Clinical Transplantation·Panpan XiaoAndy Sk Cheng
May 27, 2021·Transplantation Direct·Evelien E QuintRobert A Pol
Aug 3, 2021·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Yiman WangYvette Meuleman

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