PMID: 9186788May 1, 1997Paper

The efficacy of imipramine and psychotherapy in early-onset chronic depression: a reanalysis of the National Institute of Mental health Treatment of Depression Collaborative Research Program

Journal of Affective Disorders
V Agosti, K Ocepek-Welikson

Abstract

The authors compared the effectiveness of Cognitive Behavioral Therapy (CBT), Interpersonal Psychotherapy (IPT), Imipramine Clinical Management (ICM) to Placebo Clinical Management (PCM) for outpatients with early-onset chronic depression (N = 65) in the National Institute of Mental Health (NIMH) Treatment of Depression Collaborative Research Program (TDRP). The post-treatment depression scores of the CBT. IPT, and ICM groups were not significantly different from the PCM group. We did not find a relationship between the duration of Major Depression and response to a specific treatment. Studies are needed to determine if combining psychotherapy with medication improves social functioning and enhances the quality of life for patients with chronic depression.

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Citations

Oct 10, 2007·Der Nervenarzt·U SchweigerF Hohagen
Sep 7, 2002·Clinical Psychology Review·Kate E Hamilton, Keith S Dobson
Jul 29, 2009·Journal of Consulting and Clinical Psychology·Jay C FournierRobert Gallop
Mar 28, 2003·Journal of Personality Disorders·Simone KoolBarteld Puite
Feb 9, 2016·European Psychiatry : the Journal of the Association of European Psychiatrists·A JobstF Padberg
Aug 2, 2003·Biological Psychiatry·Albert J StunkardKelly C Allison
Mar 25, 2015·Journal of Clinical Epidemiology·Ramona MeisterLevente Kriston
Aug 1, 2015·Journal of Psychiatric Research·Stephanie M GorkaStewart A Shankman
Oct 7, 2011·Journal of General Internal Medicine·Elizabeth M YanoLisa V Rubenstein
Jul 3, 2018·Asia-Pacific Journal of Oncology Nursing·Yesol Yang, Cristina C Hendrix
Jul 23, 2013·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Jan SpijkerAnton J L M van Balkom

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