The efficacy of minocycline in inflammatory dermatoses: a case of prurigo pigmentosa of prepubescent onset in Western world

Dermatologic Therapy
Laura Cristina GironiEnrico Colombo

Abstract

We present a 21-year-old Italian girl with an 8-year history of missed diagnosed prurigo pigmentosa (PP) successfully treated with short monotherapy with minocycline. PP is an inflammatory disease characterized by recurrent pruritic erythematous papules followed by reticular hyperpigmentation usually located on the trunk. About 300 cases of PP have been described mainly in Japan, whereas only few cases have been reported in Italy. This report shows that minocycline is rapidly effective probably through its ability to scavenge reactive oxygen species and to inhibit the chemotaxis and neutrophil function. Other than its ethnic rarity, this case is very interesting because it is the third case of PP in Caucasian patient with prepubescent onset.

References

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Citations

Sep 4, 2015·American Journal of Clinical Dermatology·Bryce D BeutlerRobert A Lee
Apr 3, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·X ZengB N Cui
Oct 21, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·X ZengB N Cui
Aug 18, 2016·The American Journal of Dermatopathology·Thiago Jeunon de Sousa VargasMaria Auxiliadora Jeunon Sousa
Aug 15, 2018·Case Reports in Dermatological Medicine·N AlmaaniH Msallam
Dec 9, 2020·The American Journal of Dermatopathology·Eduardo Rozas-MuñozJuan Francisco Mir-Bonafé
Jul 10, 2019·Open Life Sciences·Xinjun Wang, Chenchen Xu

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