The efficacy of oral appliances in the treatment of persistent sleep apnea after uvulopalatopharyngoplasty

Chest
R P MillmanA E Bonitati

Abstract

Twenty-four patients who failed uvulopalatopharyngoplasty (UPPP) for obstructive sleep apnea (OSA) had an adjustable oral (Herbst) appliance made to treat the persistent apnea. Six patients discontinued the device prior to sleep evaluation. Eighteen patients had polysomnographic evaluations at baseline, post-UPPP, and with the Herbst appliance in place. The apnea-hypopnea index baseline (AHI) and arterial oxygen saturation (SaO2) nadir were 42.3+/-6.1 and 83.6+/-1.8%, respectively. There was no significant change in either parameter with surgery. With the oral appliance, the AHI fell to 15.3+/-4.4 (p < or = 0.01) and the SaO2 nadir increased to 87.9+/-1.2% (p < or = 0.05). Ten of the patients had control of the OSA with the Herbst appliance with a fall in the AHI to < 10. There were, in addition, two partial responders as defined by an AHI of <20 and a >50% fall in AHI compared with baseline and post-UPPP values. All but one of the responders and partial responders had complete resolution of subjective symptoms of daytime sleepiness with the appliance. An adjustable oral appliance appears to be an effective mode of therapy to control OSA after an unsuccessful UPPP.

References

Apr 1, 1994·American Journal of Respiratory and Critical Care Medicine·S E EveloffR P Millman
Mar 1, 1993·The American Review of Respiratory Disease·G T ClarkD Tong

❮ Previous
Next ❯

Citations

Feb 28, 2002·Sleep & Breathing = Schlaf & Atmung·A M FranssonM K Alton
Dec 1, 2006·Sleep & Breathing = Schlaf & Atmung·Victor Hoffstein
Mar 19, 2002·Sleep & Breathing = Schlaf & Atmung·Joachim T. MaurerKarl Hörmann
Mar 19, 2002·Sleep & Breathing = Schlaf & Atmung·Wolfgang Schmidt-Nowara
Jul 14, 2010·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Michael FriedmanNinos J Joseph
Jul 23, 2002·Lancet·Atul Malhotra, David P White
Feb 15, 2000·American Journal of Respiratory and Critical Care Medicine·K G HenkeS T Kuna
Jul 21, 2000·American Journal of Respiratory and Critical Care Medicine·K E BlochE W Russi
Sep 11, 2001·American Journal of Respiratory and Critical Care Medicine·K M FritschK E Bloch
Apr 17, 2002·American Journal of Respiratory and Critical Care Medicine·Boris PételleBernard Fleury
Aug 4, 2007·American Journal of Respiratory and Critical Care Medicine·Olivier M VandervekenPaul H Van de Heyning
Dec 13, 2005·Treatments in Respiratory Medicine·Andrew NgPeter A Cistulli
May 27, 2014·Sleep & Breathing = Schlaf & Atmung·Andrea De VitoClaudio Vicini
Apr 20, 2001·The American Journal of the Medical Sciences·S M Koenig
Feb 15, 2015·European Journal of Orthodontics·Natasha NazaraliPaul W Major
Jul 4, 2007·Otolaryngologic Clinics of North America·Richard L Goode
Feb 12, 2014·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Jean-Paul V Pelteret, Batmanathan D Reddy
Apr 25, 2006·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Samuel T KunaDon Frantz
Dec 20, 2007·Oral and Maxillofacial Surgery Clinics of North America·Alan A Lowe
Jul 13, 2000·Sleep·F McNamara, C E Sullivan
Aug 14, 2001·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·A GavishE Gazit
Nov 5, 2016·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Huiping LuoShankai Yin
Jun 10, 2004·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·A HoekemaL G M De Bont
Jun 13, 2003·Clinics in Chest Medicine·Kathleen A Ferguson
Aug 23, 2018·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Andrea De VitoClaudio Vicini
Feb 28, 2002·Sleep & Breathing = Schlaf & Atmung·Satoru TsuikiTakayuki Kuroda
Feb 28, 2002·Sleep & Breathing = Schlaf & Atmung·Judith OwensLeslie Berkelhammer
Jul 23, 2004·Acta Oto-laryngologica·Olivier M VandervekenPaul H Van de Heyning
Mar 21, 2018·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Vik VeerBhik Kotecha
Feb 28, 2002·Sleep & Breathing = Schlaf & Atmung·Robert R. Rogers
Apr 27, 2019·Laryngoscope Investigative Otolaryngology·Jeffrey J StanleyLouise M O'Brien
Oct 22, 2010·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Lia Rita Azeredo Bittencourt, Eliazor Campos Caixeta
Dec 10, 1999·The Journal of Prosthetic Dentistry·J R IvanhoeG R Parr
Feb 10, 2020·Respiration; International Review of Thoracic Diseases·Anneclaire V VroegopJohan A Verbraecken

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Respiration; International Review of Thoracic Diseases
Ghizlane AarabMachiel Naeije
Archives of Otolaryngology--head & Neck Surgery
Chul Hee LeeJeong-Whun Kim
Archives of Otolaryngology--head & Neck Surgery
Edward M WeaverBevan Yueh
© 2022 Meta ULC. All rights reserved