The efficiency of progesterone vaginal gel versus intramuscular progesterone for luteal phase supplementation in gonadotropin-releasing hormone antagonist cycles: a prospective clinical trial

Fertility and Sterility
Semra KahramanGuvenc Karlikaya

Abstract

We compared the efficiency of progesterone vaginal gel (PVG) with intramuscular progesterone (IMP) supplementation for luteal phase support after in vitro fertilization and embryo transfer in gonadotropin-releasing hormone (GnRH) antagonist cycles. The treatment outcomes were similar for PVG and IMP for luteal support in GnRH-antagonist protocols. With its ease of use, high tolerability by patients, and fewer side effects, PVG can be a successful alternative to IMP.

References

Feb 11, 1998·Fertility and Sterility·W E GibbonsP Kolm
Nov 24, 1999·Fertility and Sterility·S J ChantilisD D McIntire
Mar 15, 2008·Reproductive Biomedicine Online·Luca Dal PratoAndrea Borini

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Citations

Jan 29, 2016·Fertility and Sterility·Robert F Casper, Elena H Yanushpolsky
Jul 16, 2010·Fertility and Sterility·Mustafa Bahceci, Ulun Ulug
Sep 9, 2015·Acta Obstetricia Et Gynecologica Scandinavica·Walter Ciampaglia, Graciela E Cognigni
Oct 15, 2011·Gynecologic and Obstetric Investigation·Roberto Bernardo-EscuderoLucía Zambrano-Tapia
Jul 8, 2015·The Cochrane Database of Systematic Reviews·Michelle van der LindenMostafa Metwally
Apr 30, 2019·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Vlatka TomicKatarina Vucic
Feb 11, 2021·Journal of Assisted Reproduction and Genetics·Carly I HirschbergJamie A Grifo

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