PMID: 26966May 1, 1978Paper

The electrical potential difference and impedance between CSF and blood in unanesthetized man

Scandinavian Journal of Clinical and Laboratory Investigation
E SørensenH Rask-Andersen

Abstract

The electrical potential difference (PD) between cerebrospinal fluid (CSF) and blood has been studied extensively in animals. To obtain data from man the PD and impedance were recorded from the lumbar subarachnoid space of thirteen unanaesthetized patients with a presumably normal blood--brain barrier. The spontaneous PD ranged from 1 mV to 5 mV, CSF positive to blood. Hyperventilation and CO2-inhalation changed the PD with a mean slope of deltaPD/deltapHa of --4.16 mV/pH. The CSF-blood PD in unanaesthetized man is similar in direction to that found in dogs, goats and rats, but its sensitivity to change in arterial pH may be less.

References

Dec 1, 1975·Journal of Applied Physiology·S W Bledsoe, A H Mines
Apr 1, 1975·The American Journal of Physiology·E G Pavlin, T F Hornbein
Apr 1, 1975·The American Journal of Physiology·E G Pavlin, T F Hornbein
Apr 1, 1975·The American Journal of Physiology·T F Hornbein, E G Pavlin
Apr 1, 1975·The American Journal of Physiology·E G Pavlin, Hornbein ttf
Jan 1, 1971·The American Journal of Medicine·J H Christy
Aug 1, 1972·The American Journal of Physiology·T F Hornbein, S C Sorensen
Aug 1, 1974·Journal of Applied Physiology·A ChauveJ L Sasseville
Sep 1, 1971·Acta Physiologica Scandinavica·K Messeter, B K Siesjö
Oct 1, 1958·The American Journal of Physiology·R D TSCHIRGI, J L TAYLOR
Nov 1, 1963·Journal of Applied Physiology·J W SEVERINGHAUSM M SINGER
Sep 1, 1964·Journal of Neurophysiology·D HELDJ R PAPPENHEIMER

Citations

Sep 2, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Sampsa VanhataloJuha Voipio
Mar 21, 2017·PloS One·Vesa KiviniemiJuha Voipio
Mar 4, 2003·Journal of Neurophysiology·Juha VoipioKai Kaila
Apr 2, 2004·Journal of Neurophysiology·Dragos A NitaFlorin Amzica
Apr 13, 2004·Journal of Cell Science·Maria E Mycielska, Mustafa B A Djamgoz
Jan 1, 2014·Biomaterials Research·Min Sung KimJong-Chul Park

Related Concepts

Blood - Brain Barrier Anatomy
Cerebrospinal Fluid
Hydrogen-Ion Concentration
Resting Potentials
Potassium

Related Feeds

Blood Brain Barrier Chips

The blood brain barrier (BBB) is comprised of endothelial cells that regulate the influx and outflux of plasma concentrations. Lab-on-a-chip devices allow scientists to model diseases and mechanisms such as the passage of therapeutic antibodies across the BBB. Discover the latest research on BBB chips here.

Blood Brain Barrier

The blood brain barrier is a border that separates blood from cerebrospinal fluid. Discover the latest search on this highly selective semipermeable membrane here.

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.