PMID: 2112078Apr 1, 1990Paper

The electrocardiographic changes in a case of flecainide overdose

Connecticut Medicine
P K Chung, P Tuso

Abstract

Flecainide acetate is a new potent class I antiarrhythmic agent. We report serial electrocardiographic changes occurring in a case of flecainide overdose. The initial flecainide serum level was three times greater than the upper therapeutic level. The prolonged electrocardiographic time intervals (PR and QRS) decreased in correlation with falling drug levels. As the case was associated with concomitant alcohol intoxication, we speculate about the protective effect of alcohol in order to explain our patient's benign clinical course.

Related Concepts

Related Feeds

Antiarrhythmic Agents: Mechanisms of Action

Understanding the mechanism of action of antiarrhythmic agents is essential in developing new medications as treatment of cardiac arrhythmias is currently limited by the reduced availability of safe and effective drugs. Discover the latest research on Antiarrhythmic Agents: Mechanism of Action here.

Related Papers

The British Journal of Clinical Practice
J Greig, B M Groden
Annals of Internal Medicine
B R Winkelmann, H Leinberger
Journal of Accident & Emergency Medicine
E BrazilD C Bouch
© 2021 Meta ULC. All rights reserved