Jun 1, 1975

The electrolyte pattern of the gastric secretion from the vervet monkey

West African Journal of Pharmacology and Drug Research
B Gjesing

Abstract

The output of acid, chloride, sodium and potassium in gastric washings from the Vervet monkey have been measured under basal conditions and while stimulating the secretion with two doses of pentagastrin (one dose submaximal, the other dose supramaximal). The output during washings with different weak electrolyte solutions (5 mEq/1 NaC1, KCl, or HCl or 0.36 M Glycine) are compared. The results show that the composition of the secretion was independent of the composition of the rinsing fluid in the stomach except that glycine stimulated acid and potassium secretion when the monkey was not stimulated by pentagastrin. These observations and the composition of the gastric secretion of the Vervet monkey are discussed in the light of the "two-component" and "exchange" models of gastric secretion, and which compared with the gastric juice obtained from humans under similar conditions.

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Mentioned in this Paper

Chloride Ion Level
Gastric Juice
Electrolytes
Cercopithecus pygerythrus
Cercopithecus aethiops
Oral electrolyte solution
Potassium
NACC1 gene
SCN1A gene
Glycine

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