The emergence of new genes on the young therian X

Trends in Genetics : TIG
Lukasz PotrzebowskiHenrik Kaessmann

Abstract

Recent studies have revealed that our sex chromosomes differentiated relatively recently from ancestral autosomes in the common ancestor of placental and marsupial mammals (therians). Here, we show that the therian X started to accumulate new retroduplicate genes with overall sex-biased expression upon therian sex chromosome differentiation. This process reached its peak within the first approximately 90 million years of sex chromosome evolution and then leveled off. Taken together, our observations suggest that the major sex-related functional remodeling of the X was completed relatively soon after the origination of therian sex chromosomes.

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Citations

Jul 24, 2010·Genome Research·Henrik Kaessmann
Oct 26, 2011·Genome Biology and Evolution·Melissa A ToupsMatthew W Hahn
May 23, 2012·PLoS Biology·Philippe JulienHenrik Kaessmann
Nov 23, 2011·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Andrea R GschwendRay Ming
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Mar 7, 2012·Proceedings of the National Academy of Sciences of the United States of America·Eugénie PessiaGabriel A B Marais
Feb 9, 2017·Genome Biology and Evolution·Caitlyn VlasschaertDouglas A Gray
Oct 21, 2011·Nature·David BrawandHenrik Kaessmann

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