The emerging role of circulating tumor cell detection in genitourinary cancer

The Journal of Urology
Alexander C SmallMatthew D Galsky

Abstract

Circulating tumor cells are malignant cells in peripheral blood that originate from primary tumors or metastatic sites. The heterogeneous natural history and propensity for recurrence in prostate, bladder and kidney cancers are well suited for improved individualization of care using circulating tumor cells. The potential clinical applications of circulating tumor cells include early diagnosis, disease prediction and prognosis, and selection of appropriate therapies. The PubMed® and Web of Science® databases were searched using the key words circulating tumor cells, CTC, prostate, kidney, bladder, renal cell carcinoma and transitional cell carcinoma. Relevant articles and references from 1994 to 2011 were reviewed for data on the detection and significance of circulating tumor cells in genitourinary cancer. Technical challenges have previously limited the widespread introduction of circulating tumor cell detection in routine clinical care. Recently novel platforms were introduced to detect these cells that offer the promise of overcoming these limitations. We reviewed the current state of circulating tumor cell capture technologies and their clinical applications for genitourinary cancers. In genitourinary cancer circulating tu...Continue Reading

References

Jun 28, 1995·Journal of Immunological Methods·C GriwatzK S Zänker
Aug 20, 2004·The New England Journal of Medicine·Massimo CristofanilliDaniel F Hayes
Oct 27, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·W Jeffrey AllardLeon W M M Terstappen
Apr 19, 2005·Urology·Jose G MorenoLeon W M M Terstappen
Dec 26, 2006·Human Pathology·Dena MarrinucciPeter Kuhn
Apr 4, 2007·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·David R ShafferHoward I Scher
Oct 27, 2007·World Journal of Urology·Vitaly MargulisShahrokh F Shariat
Dec 7, 2007·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Daniel C DanilaHoward I Scher
Jul 2, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Steven J CohenNeal J Meropol
Oct 3, 2008·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Johann S de BonoDerek Raghavan
Oct 7, 2008·Annals of Oncology : Official Journal of the European Society for Medical Oncology·D J GallagherD F Bajorin
Dec 24, 2008·Cancer Treatment Reviews·Adrianos NezosMichael Koutsilieris
Feb 4, 2009·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Heidi SchwarzenbachKlaus Pantel
Feb 24, 2009·Proceedings of the National Academy of Sciences of the United States of America·AmirAli H TalasazRonald W Davis
Apr 29, 2009·Nature Reviews. Clinical Oncology·Klaus PantelSabine Riethdorf
Aug 8, 2009·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Karen BluemkeHelge Taubert
Sep 10, 2009·Cancer Research·Takanori TsujiGuo-fu Hu
Jan 15, 2010·Current Opinion in Genetics & Development·Shyamala Maheswaran, Daniel A Haber
Feb 5, 2010·BJU International·Angela GradilonePaola Gazzaniga
Feb 18, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Alison H M ReidJohann S de Bono
Apr 27, 2010·British Medical Bulletin·Noha GergesNada Jabado
Apr 29, 2010·Science Translational Medicine·Shannon L StottShyamala Maheswaran
Sep 15, 2010·PloS One·Elizabeth A PunnooseMark R Lackner
Sep 30, 2010·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Henry K LinRichard J Cote
Oct 12, 2010·Proceedings of the National Academy of Sciences of the United States of America·Shannon L StottMehmet Toner
Oct 20, 2010·Nature Reviews. Clinical Oncology·Michal MegoMassimo Cristofanilli
Oct 28, 2010·Biomedical Microdevices·Siyang ZhengYu-Chong Tai
Feb 9, 2011·The Journal of Cell Biology·Min YuDaniel A Haber
Jun 15, 2011·Molecular Cancer Research : MCR·Andrew J ArmstrongMariano A Garcia-Blanco

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Citations

Mar 13, 2013·Molecular Diagnosis & Therapy·Steve GoodisonVirginia Urquidi
Sep 21, 2013·Journal of Translational Medicine·Amin El-HeliebiCarolin Lackner
Mar 10, 2015·Current Urology Reports·Lorenzo MarconiMohamad E Allaf
May 7, 2013·The Journal of Urology·Guillaume PloussardUNKNOWN Committee of Cancerology of the Association of French Urology
Feb 5, 2019·Rejuvenation Research·Fengfeng CaiEwelina Biskup
Apr 17, 2021·Critical Reviews in Oncology/hematology·Tito Palmela LeitãoLuís Costa
May 27, 2021·World Journal of Surgical Oncology·Jinbo SongTiejun Yang

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