The emerging roles of eosinophils in mucosal homeostasis.

Mucosal Immunology
Kathleen ShahNicola L Harris

Abstract

Eosinophils are granulocytes, typically implicated as end-stage effector cells in type-II immune responses. They are capable of producing a wide array of pre-formed molecules which render them with vast potential to influence a wide variety of processes. Nonetheless, eosinophil research has traditionally focused on their role in anti-helminthic responses and pathophysiological processes in type-II immune disorders, such as allergy and asthma, where eosinophilia is a hallmark phenotype. However, a number of key studies over the past decade have placed this restricted view of eosinophil function into question, presenting additional evidence for eosinophils as critical regulators of various homeostatic processes including immune maintenance, organ development, and tissue regeneration.

References

Oct 1, 1966·The Journal of Experimental Medicine·R Ross, S J Klebanoff
Oct 1, 1983·The Journal of Endocrinology·A N Tchernitchin, P Galand
Feb 1, 1994·The Journal of Experimental Medicine·S DubucquoiM Capron
Jan 1, 1996·Biology of Reproduction·M C PerezC R Lyttle
Apr 1, 1997·European Journal of Obstetrics, Gynecology, and Reproductive Biology·U B KnudsenK Fredens
Nov 5, 1997·American Journal of Respiratory Cell and Molecular Biology·S OkadaK M Leiferman
May 30, 1998·Proceedings of the National Academy of Sciences of the United States of America·A N MatthewsM E Rothenberg
Nov 12, 1998·The Anatomical Record·M KatoG J Gleich
Jun 22, 1999·The Journal of Clinical Investigation·A MishraM E Rothenberg
Aug 5, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·M ThrosbyM Dardenne
Nov 4, 2000·Journal of Reproduction and Fertility·S A RobertsonK I Matthaei
Apr 9, 2001·Immunological Reviews·P S FosterD C Webb
Jun 8, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·R SalcedoJ J Oppenheim
Oct 9, 2001·The Journal of Allergy and Clinical Immunology·S M PopeM E Rothenberg
Jul 9, 2002·Breast Cancer Research : BCR·Valérie Gouon-EvansJeffrey W Pollard
Nov 12, 2003·The Journal of Allergy and Clinical Immunology·Ming YangPaul S Foster
Jan 10, 2004·The Journal of Allergy and Clinical Immunology·Amy D Klion, Thomas B Nutman
Apr 22, 2004·The Journal of Allergy and Clinical Immunology·Vladislav TemkinFrancesca Levi-Schaffer
Aug 6, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Abdelilah Soussi GounniLianyu Shan
Sep 18, 2004·Science·Marsha Wills-Karp, Christopher L Karp
Sep 18, 2004·Science·Alison A HumblesCraig Gerard
Mar 23, 2006·Annual Review of Immunology·Marc E Rothenberg, Simon P Hogan
Apr 8, 2006·American Journal of Respiratory Cell and Molecular Biology·Steven R BarthelMats W Johansson
Mar 21, 2007·Proceedings of the National Academy of Sciences of the United States of America·Laura CiarloniCathrin Brisken
Jun 6, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Sergei I OchkurNancy A Lee
Oct 24, 2007·Current Opinion in Immunology·Harsha H Kariyawasam, Douglas S Robinson
May 31, 2008·Current Opinion in Immunology·Kiyoshi Takatsu, Hiroshi Nakajima
Jun 10, 2008·The Journal of Allergy and Clinical Immunology·W Brett CherryHirohito Kita
Nov 5, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Richard AhrensSimon P Hogan
Jan 22, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Valeria FabreJudith A Appleton
Feb 24, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Brenda C TimmonsMala S Mahendroo
Jun 12, 2009·International Archives of Allergy and Immunology·Kenji MatsumotoHirohisa Saito
Oct 22, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Julia CarlensOliver Pabst
Jan 1, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Andrew L RankinStefan Pflanz
Jan 13, 2010·Immunology and Cell Biology·Lisa A Spencer, Peter F Weller
Mar 5, 2010·Nature·Daniel R NeillAndrew N J McKenzie
May 8, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J J LeeN A Lee

❮ Previous
Next ❯

Citations

Jul 29, 2020·Mucosal Immunology·Niki D Ubags
Sep 13, 2020·Parasite Immunology·Ivet A YordanovaSebastian Rausch
Oct 30, 2020·Frontiers in Endocrinology·Natália R T AmorimChristianne Bandeira-Melo
Jun 3, 2020·Allergy·Ioana AgacheMarek Jutel
Mar 28, 2021·Seminars in Immunopathology·G CoakleyN L Harris
Feb 12, 2021·American Journal of Respiratory Cell and Molecular Biology·Paulette A KrishackPhilip A Verhoef
May 1, 2021·Seminars in Immunopathology·Alessandra GurtnerIsabelle C Arnold
May 22, 2021·Seminars in Immunopathology·Nina GermicHans-Uwe Simon
Jul 30, 2021·Naunyn-Schmiedeberg's Archives of Pharmacology·Nasrin Dashti, Mitra Zarebavani
Aug 5, 2021·The Journal of Experimental Medicine·Andrea C BohrerKatrin D Mayer-Barber
Sep 7, 2021·Immunology·Iris MairKathryn J Else

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Adult Stem Cells

Adult stem cells reside in unique niches that provide vital cues for their survival, self-renewal, and differentiation. They hold great promise for use in tissue repair and regeneration as a novel therapeutic strategies. Here is the latest research.

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.