The emerging roles of ribosomal histidyl hydroxylases in cell biology, physiology and disease.

Cellular and Molecular Life Sciences : CMLS
James R BundredMathew L Coleman

Abstract

Hydroxylation is a novel protein modification catalyzed by a family of oxygenases that depend on fundamental nutrients and metabolites for activity. Protein hydroxylases have been implicated in a variety of key cellular processes that play important roles in both normal homeostasis and pathogenesis. Here, in this review, we summarize the current literature on a highly conserved sub-family of oxygenases that catalyze protein histidyl hydroxylation. We discuss the evidence supporting the biochemical assignment of these emerging enzymes as ribosomal protein hydroxylases, and provide an overview of their role in immunology, bone development, and cancer.

References

May 15, 1995·Genes & Development·T TakeuchiT Higashinakagawa
Feb 13, 2001·Trends in Biochemical Sciences·P M Clissold, C P Ponting
Jul 2, 2002·The Journal of Biological Chemistry·Makoto TsuneokaHiroshi Kimura
May 30, 2003·Molecular and Cellular Biology·Nabieh AyoubAmikam Cohen
Dec 26, 2003·The American Journal of Pathology·Kwesi TeyeHiroshi Kimura
Dec 31, 2003·Trends in Genetics : TIG·Johanna Myllyharju, Kari I Kivirikko
Jan 27, 2004·Molecular Biology of the Cell·Jens EilbrachtMarion S Schmidt-Zachmann
May 4, 2004·Critical Reviews in Biochemistry and Molecular Biology·Robert P Hausinger
May 4, 2004·Nature Reviews. Molecular Cell Biology·Christopher J Schofield, Peter J Ratcliffe
Oct 28, 2004·Biochemical Society Transactions·D E LancasterC J Schofield
Nov 10, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Makoto TsuneokaHiroshi Kimura
Apr 12, 2005·European Journal of Cell Biology·Jens EilbrachtMarion S Schmidt-Zachmann
Nov 4, 2005·Angewandte Chemie·Christopher T WalshGregory J Gatto
Mar 15, 2006·International Journal of Andrology·Makoto TsuneokaYoshiro Koda
Sep 21, 2006·Nature Reviews. Genetics·Robert J KloseYi Zhang
Feb 24, 2007·The Kurume Medical Journal·Keitaro KuratomiMasamichi Kojiro
Sep 7, 2007·Pathology International·Hironori IshizakiMasamichi Kojiro
Nov 21, 2007·Journal of Pediatric Surgery·Suguru FukahoriMasamichi Kojiro
May 24, 2008·Molecular Cell·William G Kaelin, Peter J Ratcliffe
Aug 21, 2008·The Biochemical Journal·Patrick J PollardPeter J Ratcliffe
Jun 30, 2009·Nature Immunology·Mariko OkamotoMark Bix
Sep 17, 2009·Journal of Cancer Research and Clinical Oncology·Kazutoshi KomiyaEisaburo Sueoka
Nov 17, 2009·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Kazutoshi KomiyaEisaburo Sueoka
Jan 15, 2010·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Sachiko OgasawaraHirohisa Yano
Aug 27, 2010·The Journal of Biological Chemistry·Akiko NomaTsutomu Suzuki
Mar 11, 2011·Chemical Society Reviews·Nathan R RoseChristopher J Schofield
Jul 12, 2012·Oncology Letters·Xiao-Ping TanZi-Rong Yang
Oct 30, 2012·Nature Chemical Biology·Wei GeChristopher J Schofield
Nov 20, 2012·Nature Structural & Molecular Biology·Gerard L BrienAdrian P Bracken
Dec 12, 2012·Journal of Cellular Biochemistry·Krishna M Sinha, Xin Zhou
Jun 12, 2013·Cell Structure and Function·Tetsuya MoriMakoto Tsuneoka
Aug 14, 2013·Annual Review of Pathology·Gregg L Semenza
Sep 4, 2013·The Journal of Clinical Investigation·Ming YangPatrick J Pollard
Oct 12, 2013·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Krishna M SinhaBenoit deCrombrugghe
Dec 11, 2013·PloS One·Shangli LianMark Bix

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Citations

May 7, 2020·Cancers·Nur AzizAnd Jae Youl Cho
Sep 29, 2020·Biochemical Society Transactions·Sally C Fletcher, Mathew L Coleman
Nov 30, 2021·Journal of Medicinal Chemistry·Radosław P NowakDante Rotili

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Methods Mentioned

BETA
immunoprecipitation
footprinting

Software Mentioned

iTOL
Clustal Omega

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