The end-systolic pressure-volume relationship and ventriculoarterial coupling in patients undergoing coronary artery bypass graft surgery

Acta Anaesthesiologica Scandinavica
Y KadoiN Fujita

Abstract

The end-systolic pressure-volume relationship and analysis of ventriculoarterial coupling have been established as a useful tool to determine the left ventricular performance and arterial loading conditions. The purpose of this study was to evaluate the end-systolic pressure-volume relationship and ventriculoarterial coupling in anesthetized patients with either a normal heart or coronary artery disease (CAD) using a transesophageal echocardiography (TEE) monitor. Sixteen patients with CAD and 4 patients without ischemic disease were studied. The end-systolic volume of the left ventricle was obtained by TEE, and the end-systolic pressure was obtained from the brachial arterial dicrotic pressure. In order to obtain the end-systolic pressure-volume relationship, we plotted 7 different left ventricular end-systolic pressures against the corresponding left ventricular end-systolic volumes during the pressure manipulation. The linear regression obtained by this method was designated as the end-systolic elastance (Ees). Furthermore, we calculated the effective arterial elastance (Ea) using the pressure-volume framework. We divided the patients with CAD into 3 groups: Group A: left ventricular ejection fraction (LVEF) > 50%, Group B: ...Continue Reading

References

Dec 1, 1979·The American Journal of Cardiology·J D MarshW Grossman
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Citations

Sep 12, 2003·Journal of Cardiothoracic and Vascular Anesthesia·Toshiya ShigaRyo Ogawa
Sep 14, 2007·Acta Anaesthesiologica Scandinavica·F GuarracinoC Vullo
Oct 3, 2006·Current Opinion in Anaesthesiology·J UrzuaC Saez
Sep 20, 2000·American Journal of Physiology. Heart and Circulatory Physiology·S A TrinesR Krams

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