The EndoBarrier: Duodenal-Jejunal Bypass Liner for Diabetes and Weight Loss

Gastroenterology Research and Practice
Aruchuna RubanJ P Teare

Abstract

The rapid rise of obesity and type 2 diabetes poses a global threat to healthcare and is a major cause of mortality and morbidity. Bariatric surgery has revolutionised the treatment of both these conditions but is invasive and associated with an increased risk of complications. The EndoBarrier is a device placed endoscopically in the duodenum, which is designed to mimic the effects of gastric bypass surgery with the aim of inducing weight loss and improving glycaemic control. This review outlines the current clinical evidence of the device, its efficacy, potential mechanisms of action, and utility in clinical practice.

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Citations

Sep 1, 2019·Current Diabetes Reports·Aruchuna RubanJulian P Teare
Mar 18, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·Federico SalomoneIvo Boškoski
Jun 18, 2020·Therapeutic Advances in Gastrointestinal Endoscopy·Beatrice OrlandiniGuido Costamagna
Sep 24, 2020·Therapeutic Advances in Gastrointestinal Endoscopy·Augustine TawadrosAvik Sarkar
Jun 5, 2020·Current Obesity Reports·Christine StierBarham Abu Dayyeh
Jan 1, 2021·Journal of Neurogastroenterology and Motility·Ofer Z Fass, Hiroshi Mashimo
Oct 24, 2020·Clinical and Translational Gastroenterology·Hassan GhozBarham K Abu Dayyeh
Sep 10, 2020·Techniques and Innovations in Gastrointestinal Endoscopy·Thomas R McCarty, Christopher C Thompson
Mar 9, 2021·Clinical Endoscopy·Hee Kyong NaUNKNOWN Study Group for Endoscopic Bariatric and Metabolic Therapies of the Korean Society of Gastrointestinal Endoscopy
Mar 14, 2021·Langenbeck's Archives of Surgery·Istvan Bence BalintZsolt Kaposztas
Sep 24, 2021·Annual Review of Medicine·Russell D Dolan, Allison R Schulman

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Methods Mentioned

BETA
gastric bypass
sedation

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