PMID: 2112737Jan 1, 1990Paper

The endocrinological aspects of the therapy of testicular involvement in children with acute leukemias

Pädiatrie und Grenzgebiete
W DörffelB Liedtke

Abstract

Orchidectomy or testicular irradiation with 24 to 30 Gy are recommended for testicular involvement in boys with acute lymphoblastic leukemia. But, recommended radiation doses for the only occultly involved other testis differ, i.e. they range from 12 to 24 Gy. Low dose (12 or 15 Gy) "preventive" testicular irradiation was delivered to 5 of 14 patients; only one of these 5 experienced a further testicular relapse. According to our observation, in contrast to higher doses, the dose limitation allows spontaneous pubertal development including normal testosterone production and normal development of the masculine stature.

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Related Papers

Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
E GrossB Chauvet
International Journal of Andrology
M S MortensenG Daugaard
© 2021 Meta ULC. All rights reserved