The energy sensor OsSnRK1a confers broad-spectrum disease resistance in rice

Scientific Reports
Osvaldo FilipeMonica Höfte

Abstract

Sucrose non-fermenting-1-related protein kinase-1 (SnRK1) belongs to a family of evolutionary conserved kinases with orthologs in all eukaryotes, ranging from yeasts (SnF1) to mammals (AMP-Activated kinase). These kinases sense energy deficits caused by nutrient limitation or stress and coordinate the required adaptations to maintain energy homeostasis and survival. In plants, SnRK1 is a global regulator of plant metabolism and is also involved in abiotic stress responses. Its role in the response to biotic stress, however, is only starting to be uncovered. Here we studied the effect of altered SnRK1a expression on growth and plant defense in rice. OsSnRK1a overexpression interfered with normal growth and development and increased resistance against both (hemi)biotrophic and necrotrophic pathogens, while OsSnRK1a silencing in RNAi lines increased susceptibility. OsSnRK1a overexpression positively affected the salicylic acid pathway and boosted the jasmonate-mediated defense response after inoculation with the blast fungus Pyricularia oryzae. Together these findings strongly suggest OsSnRK1a to be involved in plant basal immunity and favor a model whereby OsSnRK1a acts as a master switch that regulates growth-immunity trade-offs.

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Citations

Feb 23, 2019·Journal of Experimental Botany·Leonor MargalhaElena Baena-González
Mar 15, 2019·Journal of Experimental Botany·Muhammed Jamsheer KAshverya Laxmi
Mar 9, 2021·Frontiers in Plant Science·Jan SkalakJan Hejatko
Mar 12, 2021·Journal of Experimental Botany·Muhammed Jamsheer KVibha Srivastava
Dec 29, 2020·Current Opinion in Virology·Wei Shen, Linda Hanley-Bowdoin
Jul 22, 2021·BMC Genomics·Bruno VerstraetenTina Kyndt
Oct 7, 2021·The New Phytologist·Russell K MonsonManuel T Lerdau

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Methods Mentioned

BETA
PCR
transgenic
genotyping

Software Mentioned

Graphpad Prism
InterPro
APS assess
Simple Architecture Research Tool ( SMART )
GraphPad

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