The Enigmatic "Indirect Pathway" of the Basal Ganglia: A New Role

Neuron
Sten Grillner

Abstract

Goal-directed behavior is processed in the dorsomedial striatum. Using a probabilistic reward paradigm, Nonomura et al. (2018) show that indirect pathway neurons signal when an action is incorrect and it is time to switch strategies, while the direct pathway remains active with a correct action.

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