The Epidemiology of Incident Fracture from Cradle to Senescence

Calcified Tissue International
J A PascoM A Kotowicz

Abstract

To reduce the burden of fracture, not only does bone fragility need to be addressed, but also injury prevention. Thus, fracture epidemiology irrespective of degree of trauma is informative. We aimed to determine age-and-sex-specific fracture incidence rates for the Barwon Statistical Division, Australia, 2006-2007. Using radiology reports, incident fractures were identified for 5342 males and 4512 females, with incidence of 210.4 (95 % CI 204.8, 216.2) and 160.0 (155.3, 164.7)/10,000/year, respectively. In females, spine (clinical vertebral), hip (proximal femoral) and distal forearm fractures demonstrated a pattern of stable incidence through early adult life, with an exponential increase beginning in postmenopausal years for fractures of the forearm followed by spine and hip. A similar pattern was observed for the pelvis, humerus, femur and patella. Distal forearm, humerus, other forearm and ankle fractures showed incidence peaks during childhood and adolescence. For males, age-related changes mimicked the female pattern for fractures of the spine, hip, ribs, pelvis and humerus. Incidence at these sites was generally lower for males, particularly among the elderly. A similar childhood-adolescent peak was seen for the distal f...Continue Reading

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Citations

Dec 27, 2015·Journal of Affective Disorders·Lana J WilliamsMichael Berk
Apr 4, 2018·Journal of Paediatrics and Child Health·Elizabeth L DegabrieleSharon L Brennan-Olsen
Nov 13, 2019·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Daniel Prieto-AlhambraMartin Englund
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Jun 7, 2019·African Journal of Primary Health Care & Family Medicine·Sevani Singaram, Mergan Naidoo
Jan 3, 2021·Calcified Tissue International·Mia A PercivalNatalie K Hyde
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Oct 28, 2021·Archives of Osteoporosis·Mia A PercivalNatalie K Hyde
Nov 3, 2021·BMC Musculoskeletal Disorders·Monica C TemboJulie A Pasco

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