The epidemiology of mass breast cancer screening--a plea for a valid measure of benefit

Journal of Clinical Epidemiology
J G Schmidt

Abstract

The present paper analyses the epidemiologic effects of mass breast cancer screening. Mass mammography may possibly achieve a breast cancer mortality reduction in relative risk terms. However, this does not necessarily represent a net benefit. It is argued that the benefits and adverse effects of a screening programme must be measured in terms of absolute risks. According to this measure, the mortality reduction achieved by a mass breast screening programme is only one death per approx. 15,000 women-years. Many thousands of mammograms are needed to prevent one cancer death, and for each woman who can derive a direct benefit in terms of a prevented breast cancer death, hundreds of women have to suffer the anxiety of a positive screening mammography. Moreover, it is possible that adverse effects of breast cancer screening may contribute to mortality from other causes. Even with the assumption that screening can save lives, the net health effect of mass breast cancer screening is questionable and appears to be rather detrimental. It may be an error to recommend mass breast screening.

References

Oct 15, 1988·BMJ : British Medical Journal·J Reidy, O Hoskins
Jan 1, 1986·Journal of Chronic Diseases·A B Miller
Mar 1, 1986·Journal of Epidemiology and Community Health·C DeanS Robinson
Dec 1, 1984·Journal of Epidemiology and Community Health·U MacleanB Harnden

❮ Previous
Next ❯

Citations

Oct 1, 1992·Journal of Psychosomatic Research·J Wardle, R Pope
Mar 28, 1992·Lancet·R D Rubens, W M Gregory
Jun 12, 1993·Lancet·J M ElwoodA K Richardson
May 1, 1992·Social Science & Medicine·J HallJ Richardson
Jun 14, 1995·Gene·K DhingraG N Hortobagyi
Aug 29, 2000·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·P BoyleP Autier
Aug 26, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·A TavaniS Franceschi
Jan 1, 1995·International Journal of Technology Assessment in Health Care·I S KristiansenE M Sager
Feb 1, 2003·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·Jane WardleWendy Atkin
Feb 16, 1991·BMJ : British Medical Journal·A Rodgers
Aug 1, 1995·Journal of Epidemiology and Community Health·S SuttonJ Hunter
Dec 1, 1990·Journal of Medical Ethics·P Skrabanek
Feb 1, 1996·Postgraduate Medical Journal·C Earle, P C Hebert
Jul 1, 1996·American Journal of Public Health·J G ZapkaE Sachsse
May 1, 1992·American Journal of Surgery·D Moseson
Nov 1, 1996·Medical Hypotheses·D J Benjamin
Jan 1, 1990·Journal of Clinical Epidemiology·S Shapiro
Jan 1, 1991·Journal of Clinical Epidemiology·G M ZhengX Y Ma
Sep 13, 2005·Current Problems in Surgery·Ismail Jatoi, William F Anderson
Feb 16, 1991·BMJ : British Medical Journal
Feb 16, 1991·BMJ : British Medical Journal
Dec 23, 1998·Occupational and Environmental Medicine·P MichelozziC A Perucci
Jan 20, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·G NumicoM Merlano
Nov 1, 1995·Medical Education·P Kinderman, G Humphris
May 1, 1995·Medical Education·S J SherwoodD Bunce
Jan 3, 2013·The International Journal of Psycho-analysis·Gérard Pirlot, Maurice Corcos
May 1, 1992·The Australian Journal of Social Issues·Deborah Lupton
Jan 1, 1991·International Journal of Technology Assessment in Health Care·P Skrabanek
Jan 1, 1991·International Journal of Technology Assessment in Health Care·K N Simpson, L B Snyder
Jan 7, 1998·Health Services Management Research : an Official Journal of the Association of University Programs in Health Administration·N P RoosD Friesen

❮ Previous
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